Forcing cells into shape: the mechanics of actomyosin contractility
Actomyosin-mediated contractility is a highly conserved mechanism for generating
mechanical stress in animal cells and underlies muscle contraction, cell migration, cell …
mechanical stress in animal cells and underlies muscle contraction, cell migration, cell …
[HTML][HTML] Mastering complexity: towards bottom-up construction of multifunctional eukaryotic synthetic cells
K Göpfrich, I Platzman, JP Spatz - Trends in biotechnology, 2018 - cell.com
With the ultimate aim to construct a living cell, bottom-up synthetic biology strives to
reconstitute cellular phenomena in vitro–disentangled from the complex environment of a …
reconstitute cellular phenomena in vitro–disentangled from the complex environment of a …
Systematic design of cell membrane coating to improve tumor targeting of nanoparticles
Cell membrane (CM) coating technology is increasingly being applied in nanomedicine, but
the entire coating procedure including adsorption, rupture, and fusion is not completely …
the entire coating procedure including adsorption, rupture, and fusion is not completely …
Molecular mechanisms of cellular mechanosensing
Mechanical forces direct a host of cellular and tissue processes. Although much emphasis
has been placed on cell-adhesion complexes as force sensors, the forces must nevertheless …
has been placed on cell-adhesion complexes as force sensors, the forces must nevertheless …
Membrane tension and cytoskeleton organization in cell motility
P Sens, J Plastino - Journal of Physics: Condensed Matter, 2015 - iopscience.iop.org
Cell membrane shape changes are important for many aspects of normal biological function,
such as tissue development, wound healing and cell division and motility. Various disease …
such as tissue development, wound healing and cell division and motility. Various disease …
Giant vesicles as cell models
SF Fenz, K Sengupta - Integrative Biology, 2012 - academic.oup.com
Tremendous progress has been made in recent years in understanding the working of the
living cell, including its micro-anatomy, signalling networks, and regulation of genes …
living cell, including its micro-anatomy, signalling networks, and regulation of genes …
Protein reconstitution inside giant unilamellar vesicles
T Litschel, P Schwille - Annual Review of Biophysics, 2021 - annualreviews.org
Giant unilamellar vesicles (GUVs) have gained great popularity as mimicries for cellular
membranes. As their sizes are comfortably above the optical resolution limit, and their lipid …
membranes. As their sizes are comfortably above the optical resolution limit, and their lipid …
Actomyosin-driven division of a synthetic cell
One of the major challenges of bottom-up synthetic biology is rebuilding a minimal cell
division machinery. From a reconstitution perspective, the animal cell division apparatus is …
division machinery. From a reconstitution perspective, the animal cell division apparatus is …
Composite branched and linear F-actin maximize myosin-induced membrane shape changes in a biomimetic cell model
R Sakamoto, MP Murrell - Communications Biology, 2024 - nature.com
The architecture of the actin cortex determines the generation and transmission of stresses,
during key events from cell division to migration. However, its impact on myosin-induced cell …
during key events from cell division to migration. However, its impact on myosin-induced cell …
Geometric trade-off between contractile force and viscous drag determines the actomyosin-based motility of a cell-sized droplet
Cell migration in confined environments is fundamental for diverse biological processes
from cancer invasion to leukocyte trafficking. The cell body is propelled by the contractile …
from cancer invasion to leukocyte trafficking. The cell body is propelled by the contractile …