Forcing cells into shape: the mechanics of actomyosin contractility

M Murrell, PW Oakes, M Lenz, ML Gardel - Nature reviews Molecular …, 2015 - nature.com
Actomyosin-mediated contractility is a highly conserved mechanism for generating
mechanical stress in animal cells and underlies muscle contraction, cell migration, cell …

[HTML][HTML] Mastering complexity: towards bottom-up construction of multifunctional eukaryotic synthetic cells

K Göpfrich, I Platzman, JP Spatz - Trends in biotechnology, 2018 - cell.com
With the ultimate aim to construct a living cell, bottom-up synthetic biology strives to
reconstitute cellular phenomena in vitro–disentangled from the complex environment of a …

Systematic design of cell membrane coating to improve tumor targeting of nanoparticles

L Liu, D Pan, S Chen, MV Martikainen… - Nature …, 2022 - nature.com
Cell membrane (CM) coating technology is increasingly being applied in nanomedicine, but
the entire coating procedure including adsorption, rupture, and fusion is not completely …

Molecular mechanisms of cellular mechanosensing

T Luo, K Mohan, PA Iglesias, DN Robinson - Nature materials, 2013 - nature.com
Mechanical forces direct a host of cellular and tissue processes. Although much emphasis
has been placed on cell-adhesion complexes as force sensors, the forces must nevertheless …

Membrane tension and cytoskeleton organization in cell motility

P Sens, J Plastino - Journal of Physics: Condensed Matter, 2015 - iopscience.iop.org
Cell membrane shape changes are important for many aspects of normal biological function,
such as tissue development, wound healing and cell division and motility. Various disease …

Giant vesicles as cell models

SF Fenz, K Sengupta - Integrative Biology, 2012 - academic.oup.com
Tremendous progress has been made in recent years in understanding the working of the
living cell, including its micro-anatomy, signalling networks, and regulation of genes …

Protein reconstitution inside giant unilamellar vesicles

T Litschel, P Schwille - Annual Review of Biophysics, 2021 - annualreviews.org
Giant unilamellar vesicles (GUVs) have gained great popularity as mimicries for cellular
membranes. As their sizes are comfortably above the optical resolution limit, and their lipid …

Actomyosin-driven division of a synthetic cell

L Baldauf, L Van Buren, F Fanalista… - ACS Synthetic …, 2022 - ACS Publications
One of the major challenges of bottom-up synthetic biology is rebuilding a minimal cell
division machinery. From a reconstitution perspective, the animal cell division apparatus is …

Composite branched and linear F-actin maximize myosin-induced membrane shape changes in a biomimetic cell model

R Sakamoto, MP Murrell - Communications Biology, 2024 - nature.com
The architecture of the actin cortex determines the generation and transmission of stresses,
during key events from cell division to migration. However, its impact on myosin-induced cell …

Geometric trade-off between contractile force and viscous drag determines the actomyosin-based motility of a cell-sized droplet

R Sakamoto, Z Izri, Y Shimamoto… - Proceedings of the …, 2022 - National Acad Sciences
Cell migration in confined environments is fundamental for diverse biological processes
from cancer invasion to leukocyte trafficking. The cell body is propelled by the contractile …