The key points in the pre-analytical procedures of blood and urine samples in metabolomics studies

H Bi, Z Guo, X Jia, H Liu, L Ma, L Xue - Metabolomics, 2020 - Springer
Background Metabolomics provides measurement of numerous metabolites in human
samples, which can be a useful tool in clinical research. Blood and urine are regarded as …

The impact of pre‐analytical variations on biochemical analytes stability: A systematic review

M Hedayati, SA Razavi, S Boroomand… - Journal of Clinical …, 2020 - Wiley Online Library
Objective A common problem in clinical laboratories is maintaining the stability of analytes
during pre‐analytical processes. The aim of this study was to systematically summarize the …

The effect of storage time and freeze-thaw cycles on the stability of serum samples

S Cuhadar, M Koseoglu, A Atay, A Dirican - Biochemia medica, 2013 - hrcak.srce.hr
Introduction: Optimal storage of serum specimens in central laboratories for a long period for
multicenter reference interval studies, or epidemiologic studies remains to be determined …

The effects of storage temperature and duration of blood samples on DNA and RNA qualities

LH Huang, PH Lin, KW Tsai, LJ Wang, YH Huang… - PloS one, 2017 - journals.plos.org
DNA and RNA samples from blood are the common examination target for non-invasive
physical tests and/or biomedical studies. Since high-quality DNA and RNA samples …

Preanalytical phase–a continuous challenge for laboratory professionals

AM Simundic, G Lippi - Biochemia medica, 2012 - hrcak.srce.hr
Sažetak Preanalytical phase is the most vulnerable part of the total testing process and is
considered to be among the greatest challenges to the laboratory professionals. However …

[HTML][HTML] The CRESS checklist for reporting stability studies: on behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working …

M Cornes, AM Simundic, J Cadamuro… - Clinical Chemistry and …, 2021 - degruyter.com
To ensure that clinical laboratories produce results that are both accurate and of clinical
utility it is essential that only samples of adequate quality are analysed. Although various …

Study of the stability of various biochemical analytes in samples stored at different predefined storage conditions at an accredited laboratory of India

K Kachhawa, P Kachhawa, M Varma… - Journal of laboratory …, 2017 - thieme-connect.com
Background: Storage of serum and other blood products is often necessary in laboratories
because of technical issues or to preserve samples for subsequent research purposes. The …

Laboratory sample stability. Is it possible to define a consensus stability function? An example of five blood magnitudes

R Gómez Rioja, D Martínez Espartosa… - Clinical Chemistry and …, 2018 - degruyter.com
Background: The stability limit of an analyte in a biological sample can be defined as the
time required until a measured property acquires a bias higher than a defined specification …

A critical evaluation of wet biomarkers for Huntington's disease: current status and ways forward

E Silajdžić, M Björkqvist - Journal of Huntington's disease, 2018 - content.iospress.com
There is an unmet clinical need for objective biomarkers to monitor disease progression and
treatment response in Huntington's disease (HD). The aim of this review is, therefore, to …

Influence of the collection tube on metabolomic changes in serum and plasma

MA López-Bascón, F Priego-Capote, A Peralbo-Molina… - Talanta, 2016 - Elsevier
Major threats in metabolomics clinical research are biases in sampling and preparation of
biological samples. Bias in sample collection is a frequently forgotten aspect responsible for …