Lithium (Li+) is a first option treatment for adult acute episodes of Bipolar Disorder (BD) and
for the prophylaxis of new depressed or manic episodes. It is also the preferred choice as …

Here an overview is provided on therapeutic/neuroprotective effects of Lithium (Li+) in
neurodegenerative and psychiatric disorders focusing on the conspicuous action of Li+ …

Substantial data exists demonstrating the importance of the amygdala and the locus
ceruleus (LC) in responding to stress, aversive memory formation, and the development of …

Current psychiatry relies on a purely categorical paradigm for diagnosis of mental disorders
that profoundly impacts research and clinical practice. However, high comorbidity rates and …

Lithium is an effective drug for both the treatment and prophylaxis of bipolar disorder.
However, the precise mechanism of lithium action is not yet well understood. Extensive …

There are numerous lines of evidence pointing to norepinephrine being of crucial
importance in pathophysiology of anxiety and mood disorders. First, norepinephrine …

We investigated lithium-induced changes in norepinephrine (NE) catabolism. NE and its
major metabolites 3-methoxy-4-hydroxyphenylglycol (MHPG) and 3, 4-dihydroxyphenyl …

Introduction: The re-establishment of electrode position after microiontophoresis with multi-
barrelled electrodes has always been a complicated and mostly inaccurate procedure. The …

Lithium is an effective drug for both treatment and prophylaxis of affective disorder. The
mechanism of lithium action is, however, still unknown. Over the past 50 years pre-clinical …

The hippocampal formation, and the ventral subiculum (vSub), constitute a central node in
mediating the forebrain's stress response, particularly to psychogenic stressors. The vSub …