Background Patients suffering from malignant gliomas have a poor prognosis. For the
surgical treatment of these tumors, 5‐aminolevulinic acid (5‐ALA) has become a new …

Hypericin (4, 5, 7, 4′, 5′, 7′-hexahydroxy-2, 2′-dimethylnaphtodianthrone) is a naturally
occurring chromophore found in some species of the genus Hypericum, especially …

The promise of dendritic cell (DC)–based immunotherapy has been established by two
decades of translational research. Of the four malignancies most targeted with clinical DC …

Background: Hypericin is a prominent secondary metabolite mainly existing in genus
Hypericum. It has become a research focus for a quiet long time owing to its extensively …

Background Fluorescence-guided surgery (FGS) is a technique used to enhance
visualization of tumor margins in order to increase the extent of tumor resection in glioma …

Objective Fluorescence guidance has a demonstrated potential in maximizing the extent of
high-grade glioma resection. Different fluorophores (fluorescent biomarkers), including 5 …

Objective. High dose fluorescein sodium has been utilized for fluorescence-guided tumor
resection with conflicting reports on the efficacy of this procedure. The aim of this study was …

Since centuries, natural compounds from plants, animals and microorganisms were used in
medicinal traditions to treat various diseases without a solid scientific basis. Recent studies …

Introduction The prognosis of patients with Oral squamous cell carcinoma (OSCC) are
directly related to the stage of development of the tumor at the time of diagnosis, but it is …

Hypericum perforatum L. is an ethnomedicine with a popular remedial legacy; especially of
antidepressant and wound healing properties. Rigorous preclinical and clinical research …