[HTML][HTML] Silencing and transcriptional regulation of endogenous retroviruses: an overview
FK Geis, SP Goff - Viruses, 2020 - mdpi.com
Almost half of the human genome is made up of transposable elements (TEs), and about 8%
consists of endogenous retroviruses (ERVs). ERVs are remnants of ancient exogenous …
consists of endogenous retroviruses (ERVs). ERVs are remnants of ancient exogenous …
Transposable elements as new players in neurodegenerative diseases
C Ravel‐Godreuil, R Znaidi, T Bonnifet, RL Joshi… - FEBS …, 2021 - Wiley Online Library
Neurodegenerative diseases (NDs), including the most prevalent Alzheimer's disease and
Parkinson disease, share common pathological features. Despite decades of gene‐centric …
Parkinson disease, share common pathological features. Despite decades of gene‐centric …
Prenatal valproate in rodents as a tool to understand the neural underpinnings of social dysfunctions in autism spectrum disorder
AM Tartaglione, S Schiavi, G Calamandrei, V Trezza - Neuropharmacology, 2019 - Elsevier
Impairments in social interaction and verbal and non verbal communication are among the
main features of Autism Spectrum Disorder (ASD). The causes of ASD are still unknown but …
main features of Autism Spectrum Disorder (ASD). The causes of ASD are still unknown but …
[HTML][HTML] Human endogenous retroviruses in development and disease
J Mao, Q Zhang, YS Cong - Computational and Structural Biotechnology …, 2021 - Elsevier
Human endogenous retroviruses (HERVs) represent∼ 8% of human genome, deriving from
exogenous retroviral infections of germ line cells occurred millions of years ago and being …
exogenous retroviral infections of germ line cells occurred millions of years ago and being …
[HTML][HTML] Transposable elements and their epigenetic regulation in mental disorders: current evidence in the field
B Misiak, L Ricceri, MM Sąsiadek - Frontiers in genetics, 2019 - frontiersin.org
Transposable elements (TEs) are highly repetitive DNA sequences in the human genome
that are the relics of previous retrotransposition events. Although the majority of TEs are …
that are the relics of previous retrotransposition events. Although the majority of TEs are …
[HTML][HTML] A retrotransposon storm marks clinical phenoconversion to late-onset Alzheimer's disease
F Macciardi, M Giulia Bacalini, R Miramontes… - GeroScience, 2022 - Springer
Recent reports have suggested that the reactivation of otherwise transcriptionally silent
transposable elements (TEs) might induce brain degeneration, either by dysregulating the …
transposable elements (TEs) might induce brain degeneration, either by dysregulating the …
[HTML][HTML] Human endogenous retroviruses as gene expression regulators: insights from animal models into human diseases
S Durnaoglu, SK Lee, J Ahnn - Molecules and cells, 2021 - Elsevier
The human genome contains many retroviral elements called human endogenous
retroviruses (HERVs), resulting from the integration of retroviruses throughout evolution …
retroviruses (HERVs), resulting from the integration of retroviruses throughout evolution …
Human endogenous retroviruses role in cancer cell stemness
C Matteucci, E Balestrieri, A Argaw-Denboba… - Seminars in cancer …, 2018 - Elsevier
Cancer incidence and mortality, metastasis, drug resistance and recurrence are still the
critical issues of oncological diseases. In this scenario, increasing scientific evidences …
critical issues of oncological diseases. In this scenario, increasing scientific evidences …
Retrotransposon-induced mosaicism in the neural genome
GO Bodea, EGZ McKelvey, GJ Faulkner - Open Biology, 2018 - royalsocietypublishing.org
Over the past decade, major discoveries in retrotransposon biology have depicted the
neural genome as a dynamic structure during life. In particular, the retrotransposon LINE-1 …
neural genome as a dynamic structure during life. In particular, the retrotransposon LINE-1 …
[HTML][HTML] Type W human endogenous retrovirus (HERV-W) integrations and their mobilization by L1 machinery: contribution to the human transcriptome and impact on …
N Grandi, E Tramontano - Viruses, 2017 - mdpi.com
Human Endogenous Retroviruses (HERVs) are ancient infection relics constituting~ 8% of
our DNA. While HERVs' genomic characterization is still ongoing, impressive amounts of …
our DNA. While HERVs' genomic characterization is still ongoing, impressive amounts of …