Potential role of flavonoids in treating chronic inflammatory diseases with a special focus on the anti-inflammatory activity of apigenin

R Ginwala, R Bhavsar, DGI Chigbu, P Jain, ZK Khan - Antioxidants, 2019 - mdpi.com
Inflammation has been reported to be intimately linked to the development or worsening of
several non-infectious diseases. A number of chronic conditions such as cancer, diabetes …

[HTML][HTML] Cytotoxicity of dietary flavonoids on different human cancer types

K Sak - Pharmacognosy reviews, 2014 - ncbi.nlm.nih.gov
Flavonoids are ubiquitous in nature. They are also in food, providing an essential link
between diet and prevention of chronic diseases including cancer. Anticancer effects of …

[HTML][HTML] Estrogenic flavonoids and their molecular mechanisms of action

R Kiyama - The Journal of Nutritional Biochemistry, 2023 - Elsevier
Flavonoids are a major group of phytoestrogens associated with physiological effects, and
ecological and social impacts. Although the estrogenic activity of flavonoids was reported by …

Apigenin: a promising molecule for cancer prevention

S Shukla, S Gupta - Pharmaceutical research, 2010 - Springer
Apigenin, a naturally occurring plant flavone, abundantly present in common fruits and
vegetables, is recognized as a bioactive flavonoid shown to possess anti-inflammatory …

Estrogenic endocrine disruptors: Molecular mechanisms of action

R Kiyama, Y Wada-Kiyama - Environment International, 2015 - Elsevier
A comprehensive summary of more than 450 estrogenic chemicals including estrogenic
endocrine disruptors is provided here to understand the complex and profound impact of …

Salt-tolerant plants, halophytes, as renewable natural resources for cancer prevention and treatment: roles of phenolics and flavonoids in immunomodulation and …

HA Mohammed, AH Emwas, RA Khan - International Journal of Molecular …, 2023 - mdpi.com
Halophytes and xerophytes, plants with adequate tolerance to high salinity with strong ability
to survive in drought ecosystem, have been recognized for their nutritional and medicinal …

[HTML][HTML] ERβ impedes prostate cancer EMT by destabilizing HIF-1α and inhibiting VEGF-mediated snail nuclear localization: implications for Gleason grading

P Mak, I Leav, B Pursell, D Bae, X Yang, CA Taglienti… - Cancer cell, 2010 - cell.com
High Gleason grade prostate carcinomas are aggressive, poorly differentiated tumors that
exhibit diminished estrogen receptor β (ERβ) expression. We report that a key function of …

Rationalizing the therapeutic potential of apigenin against cancer

SA Ahmed, D Parama, E Daimari, S Girisa, K Banik… - Life sciences, 2021 - Elsevier
Background Despite the remarkable advances made in the diagnosis and treatment of
cancer during the past couple of decades, it remains the second largest cause of mortality in …

[HTML][HTML] Phytoestrogens and breast cancer: In vitro anticancer activities of isoflavones, lignans, coumestans, stilbenes and their analogs and derivatives

P Basu, C Maier - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Breast cancer is one of the leading causes of cancer-related morbidity and mortality among
women worldwide. Phytoestrogens, plant-derived polyphenols that structurally and …

South African herbal teas: Aspalathus linearis, Cyclopia spp. and Athrixia phylicoides—A review

E Joubert, WCA Gelderblom, A Louw… - Journal of …, 2008 - Elsevier
Rooibos (Aspalathus linearis (Brum. f) Dahlg.) and honeybush (Cyclopia Vent. species) are
popular indigenous South African herbal teas enjoyed for their taste and aroma. Traditional …