Identification and evaluation of bioactive natural products as potential inhibitors of human microtubule affinity-regulating kinase 4 (MARK4)

T Mohammad, FI Khan, KA Lobb, A Islam… - Journal of …, 2019 - Taylor & Francis
Microtubule affinity-regulating kinase 4 (MARK4) has recently been identified as a potential
drug target for several complex diseases including cancer, diabetes and neurodegenerative …

Evaluation of pyrazolopyrimidine derivatives as microtubule affinity regulating kinase 4 inhibitors: towards therapeutic management of Alzheimer's disease

AAT Naqvi, DS Jairajpuri, OMA Noman… - Journal of …, 2020 - Taylor & Francis
Microtubule affinity regulating kinase 4 (MARK4) plays essential role in the tau-assisted
regulation of microtubule dynamics. Over expression of MARK4 causes early …