[HTML][HTML] Advancing therapeutic strategies for Epstein-Barr virus-associated malignancies through lytic reactivation
H Tan, Y Gong, Y Liu, J Long, Q Luo, OD Faleti… - Biomedicine & …, 2023 - Elsevier
Epstein-Barr virus (EBV) is a widespread human herpes virus associated with lymphomas
and epithelial cell cancers. It establishes two separate infection phases, latent and lytic, in …
and epithelial cell cancers. It establishes two separate infection phases, latent and lytic, in …
The interaction between Epstein–Barr virus and multiple sclerosis genetic risk loci: insights into disease pathogenesis and therapeutic opportunities
A Afrasiabi, C Ahlenstiel… - Clinical & …, 2023 - Wiley Online Library
Multiple sclerosis (MS) is a chronic neurodegenerative autoimmune disease, characterised
by the demyelination of neurons in the central nervous system. Whilst it is unclear what …
by the demyelination of neurons in the central nervous system. Whilst it is unclear what …
Epstein-Barr virus infection as potential indicator of the occurrence and clinical presentation of systemic lupus erythematosus
A Banko, A Cirkovic, R Miskovic, I Jeremic… - Frontiers in …, 2023 - frontiersin.org
Introduction The relationship between Systemic lupus erythematosus (SLE) and Epstein-
Barr virus (EBV) infection has been suggested for decades, but the underlying mechanism of …
Barr virus (EBV) infection has been suggested for decades, but the underlying mechanism of …
Multiple sclerosis patient-derived spontaneous B cells have distinct EBV and host gene expression profiles in active disease
SS Soldan, C Su, MC Monaco, L Yoon, T Kannan… - Nature …, 2024 - nature.com
Epstein–Barr virus (EBV) is an aetiologic risk factor for the development of multiple sclerosis
(MS). However, the role of EBV-infected B cells in the immunopathology of MS is not well …
(MS). However, the role of EBV-infected B cells in the immunopathology of MS is not well …
Understanding the neurotrophic virus mechanisms and their potential effect on systemic lupus erythematosus development
FR Uribe, VPI González, AM Kalergis, JA Soto… - Brain Sciences, 2024 - mdpi.com
Central nervous system (CNS) pathologies are a public health concern, with viral infections
one of their principal causes. These viruses are known as neurotropic pathogens …
one of their principal causes. These viruses are known as neurotropic pathogens …
Genetic associations and differential mRNA expression levels of host genes suggest a viral trigger for endemic pemphigus foliaceus
VBB Hoch, AF Kohler, DG Augusto, SC Lobo-Alves… - Viruses, 2022 - mdpi.com
The long search for the environmental trigger of the endemic pemphigus foliaceus (EPF,
fogo selvagem) has not yet resulted in any tangible findings. Here, we searched for genetic …
fogo selvagem) has not yet resulted in any tangible findings. Here, we searched for genetic …
[HTML][HTML] Haplotype-specific chromatin looping reveals genetic interactions of regulatory regions modulating gene expression in 8p23. 1
M Saint Just Ribeiro, P Tripathi, B Namjou… - Frontiers in …, 2022 - frontiersin.org
A major goal of genetics research is to elucidate mechanisms explaining how genetic
variation contributes to phenotypic variation. The genetic variants identified in genome-wide …
variation contributes to phenotypic variation. The genetic variants identified in genome-wide …
Association of Human Leucocyte Antigen Class II, with viral load and immune response to Epstein–Barr virus in adult and pediatric Systemic lupus erythematosus …
Objective Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease, which
is known to be associated with HLA-DRB1 and Epstein–Barr virus (EBV) infection. In the …
is known to be associated with HLA-DRB1 and Epstein–Barr virus (EBV) infection. In the …
[HTML][HTML] Modeling of horizontal pleiotropy identifies possible causal gene expression in systemic lupus erythematosus
Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune condition with
complex causes involving genetic and environmental factors. While genome-wide …
complex causes involving genetic and environmental factors. While genome-wide …
A Framework to Overcome Challenges in the Management of Infections in Patients with Systemic Lupus Erythematosus
M Rao, J Mikdashi - Open Access Rheumatology: Research and …, 2023 - Taylor & Francis
Infections remain one of the leading causes of death in systemic lupus erythematosus (SLE),
despite awareness of factors contributing to increased susceptibility to infectious diseases in …
despite awareness of factors contributing to increased susceptibility to infectious diseases in …