Adipose‐derived stem cells (ADSCs) can maintain self‐renewal and enhanced
multidifferentiation potential through the release of a variety of paracrine factors and …

Regenerative therapies for bone and cartilage injuries are currently unable to replicate the
complex microenvironment of native tissue. There are many tissue engineering approaches …

As cartilage tissue lacks the innate ability to mount an adequate regeneration response,
damage to it is detrimental to the quality of life of the subject. The emergence of three …

Decellularized materials (DMs) are attracting more and more attention because of their
native structures, comparatively high bioactivity, low immunogenicity and good …

Articular cartilage (AC) is an avascular and flexible connective tissue located on the bone
surface in the diarthrodial joints. AC defects are common in the knees of young and …

Much research is currently ongoing into new therapies for cartilage defect repair with new
biomaterials frequently appearing which purport to have significant regenerative capacity …

Freshly isolated stromal cells can potentially be used as an alternative to in vitro expanded
cells in regenerative medicine. Their use requires the development of bioactive hydrogels or …

Engineering constructs that mimic the complex structure, composition and biomechanics of
the articular cartilage represents a promising route to joint regeneration. Such tissue …

Biological scaffolds generated from tissue-derived extracellular matrix (ECM) are commonly
used clinically for soft tissue regeneration. Such biomaterials can enhance tissue-specific …

The infrapatellar fat pad (IFP) has until recently been viewed as a densely vascular and
innervated intracapsular/extrasynovial tissue with biomechanical roles in the anterior …