Colorectal cancer (CRC) is one of the most common cancers worldwide and a leading
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …

Individualizing patient treatment is a core objective of the medical field. Reaching this
objective has been elusive owing to the complex set of factors contributing to both disease …

Circulating tumor cells (CTCs), shed by primary malignancies, function as" seeds" for distant
metastasis. However, it is still largely unknown how CTCs escape immune surveillance …

Simple Summary Colorectal cancer (CRC) is the third most common cancer worldwide.
Metastasis to secondary organs, such as the liver and lungs, is a key driver of CRC-related …

New non-invasive approaches that can complement and improve on current strategies for
colorectal cancer (CRC) screening and management are urgently needed. A growing …

Immunotherapy, especially anti-programmed cell death protein 1/programmed cell death
ligand 1 (PD-1/PD-L1) treatment has significantly improved the survival of non-small cell …

Circulating tumor cells (CTC) in the blood of cancer patients are regarded as potential
metastatic seeds, and their detailed characterization holds great promises for more exact …

Background: Colorectal cancer (CRC) follows a protracted stepwise progression, from
benign adenomas to malignant adenocarcinomas. If detected early, 90% of deaths are …

Single cell messenger RNA sequencing (scRNA-seq) provides a window into transcriptional
landscapes in complex tissues. The recent introduction of droplet based transcriptomics …

Despite major therapeutic progress, most advanced solid tumors are still incurable. Cancer
interception is the active way to combat cancer onset, and development of this approach …