Lung cancer in Europe in 2000: epidemiology, prevention, and early detection

JE Tyczynski, F Bray, DM Parkin - The lancet oncology, 2003 - thelancet.com
Lung cancer is the most common cancer in the world. In men, the highest incidence rates
are seen in Europe (especially eastern Europe) and North America. In women, high …

Progress in chemoprevention drug development: the promise of molecular biomarkers for prevention of intraepithelial neoplasia and cancer—a plan to move forward

GJ Kelloff, SM Lippman, AJ Dannenberg… - Clinical Cancer …, 2006 - AACR
This article reviews progress in chemopreventive drug development, especially data and
concepts that are new since the 2002 AACR report on treatment and prevention of …

Phenethyl Isothiocyanate and Sulforaphane and their N-Acetylcysteine Conjugates Inhibit Malignant Progression of Lung Adenomas Induced by Tobacco …

CC Conaway, CX Wang, B Pittman, YM Yang… - Cancer research, 2005 - AACR
We have shown previously that naturally occurring isothiocyanates derived from cruciferous
vegetables and their N-acetylcysteine conjugates inhibit lung adenoma formation induced …

Chemoprevention of lung carcinogenesis in addicted smokers and ex-smokers

SS Hecht, F Kassie, DK Hatsukami - Nature Reviews Cancer, 2009 - nature.com
Chemoprevention of lung carcinogenesis is one approach to controlling the epidemic of
lung cancer caused by cigarette smoking. The target for chemoprevention should be the …

Modulation of microRNA expression by budesonide, phenethyl isothiocyanate and cigarette smoke in mouse liver and lung

A Izzotti, P Larghero, C Cartiglia, M Longobardi… - …, 2010 - academic.oup.com
Although microRNAs (miRNA) have extensively been investigated in cancer research, less
attention has been paid to their regulation by carcinogens and/or protective factors in early …

A randomized phase IIb trial of pulmicort turbuhaler (budesonide) in people with dysplasia of the bronchial epithelium

S Lam, JC LeRiche, A McWilliams, C MacAulay… - Clinical Cancer …, 2004 - AACR
Purpose: Preclinical studies suggest that inhaled budesonide may be an effective
chemopreventive agent for lung cancer. We conducted a phase IIb study to determine the …

Chemoprevention of lung cancer: diagnosis and management of lung cancer: American College of Chest Physicians evidence-based clinical practice guidelines

E Szabo, JT Mao, S Lam, ME Reid, RL Keith - Chest, 2013 - Elsevier
Background Lung cancer is the most common cause of cancer death in men and women in
the United States. Cigarette smoking is the main risk factor. Former smokers are at a …

Chemoprevention of oral cancer by lyophilized strawberries

BC Casto, TJ Knobloch, RL Galioto, Z Yu… - Anticancer …, 2013 - ar.iiarjournals.org
Background/Aim: Oral cancer represents approximately 2.5% of all cancers in the United
States, with five-and 10-year survival rates of 62% and 51%. In the present study, lyophilized …

Decreased colorectal cancer and adenoma risk in patients with microscopic colitis

EF Yen, B Pokhrel, LK Bianchi, HK Roy, H Du… - Digestive diseases and …, 2012 - Springer
Introduction Microscopic colitis is currently considered to harbor no increased risk for
colorectal cancer, based on a few small studies with limited long-term follow-up. Our aim …

Role of inflammation in mouse lung tumorigenesis: a review

AM Malkinson - Experimental lung research, 2004 - Taylor & Francis
Peritumoral and intratumoral macrophages are associated with human and mouse lung
cancer. The mouse model allows manipulation of the macrophage population to …