Eukaryotic genomes are prevalently transcribed into many types of RNAs that translate into
proteins or execute gene regulatory functions. Many RNAs associate with chromatin directly …

Epitranscriptomic modification of RNA regulates human development, health, and disease.
The true diversity of the transcriptome in breast cancer including chemical modification of …

This comprehensive Review delves into the chemical principles governing RNA-mediated
crowding events, commonly referred to as granules or biological condensates. We explore …

RNA was shown to have a more substantial role in the regulation of diverse cellular
processes than anticipated until recently. Answers to questions what is the structure of …

Summary lncRNA research is passing the stage of enumerating lncRNAs or recording
simplified on-off expression switches. Mechanistic analyses are starting to reveal …

Protein–RNA complexes exist in many forms within the cell, from stable machines such as
the ribosome to transient assemblies like the spliceosome. All protein–RNA assemblies rely …

Abstract N6-methyladenosine (m6A) is one of the epigenetic modifications of RNA. The
addition of this chemical mark to RNA molecules regulates gene expression by affecting the …

Telomerase-negative tumors maintain telomere length by alternative lengthening of
telomeres (ALT), but the underlying mechanism behind ALT remains poorly understood. A …

RNA methylations play critical roles in RNA processes, including RNA splicing, nuclear
export, nonsense-mediated RNA decay, and translation. Regulators of RNA methylations …

RNA N 6-methyladenosine (m 6 A) is the most abundant internal mRNA modification and
forms part of an epitranscriptomic system that modulates RNA function. m 6 A is reversibly …