In the last few decades, targeting cancer by the use of dietary phytochemicals has gained
enormous attention. The plausible reason and believe or mind set behind this fact is …

Infections caused by Candida albicans, often refractory and with high morbidity and
mortality, cause a heavy burden on the public health while the current antifungal drugs are …

Although effective drugs have been developed, including 5-fluorouracil (5-FU), advanced
colorectal cancer (CRC) shows low therapeutic sensitivity resulting from the development of …

Human triple negative breast cancer cells, MDA-MB-231, show typical epithelial to
mesenchymal transition associated with cancer progression. Mitochondria play a major role …

Background/Aims: Protodioscin (PD) is a steroidal saponin with anti-cancer effects on a
number of cancer cells, but the anti-tumor effects and mechanism of action of PD on human …

Silybum marianum commonly known as milk thistle is an important medicinal plant used for
dyslipidemia, hyperlipidemia, cAMP phosphodiesterase inhibition, leukotriene synthesis …

Induction of lethal autophagy has become a strategy to eliminate glioma cells, but it remains
elusive whether autophagy contributes to cell death via causing mitochondria damage and …

A new secalonic acid derivative, F-7 (1), was isolated from the endophytic Aspergillus
aculeatus MBT 102, associated with Rosa damascena. The planar structure of 1 was …

Background Silibinin, the principal flavonoid derived from milk thistle seeds, has been
demonstrated to have strong inhibitory effects against human malignancies. The inhibitory …

Nonalcoholic fatty liver disease (NAFLD) is an important health problem. The prevalence of
NAFLD is increasing, especially in the Western countries. Although there are several …