[HTML][HTML] The trRosetta server for fast and accurate protein structure prediction
The trRosetta (transform-restrained Rosetta) server is a web-based platform for fast and
accurate protein structure prediction, powered by deep learning and Rosetta. With the input …
accurate protein structure prediction, powered by deep learning and Rosetta. With the input …
[HTML][HTML] Critical assessment of methods for predicting the 3D structure of proteins and protein complexes
SJ Wodak, S Vajda, MF Lensink… - Annual review of …, 2023 - annualreviews.org
Advances in a scientific discipline are often measured by small, incremental steps. In this
review, we report on two intertwined disciplines in the protein structure prediction field …
review, we report on two intertwined disciplines in the protein structure prediction field …
Targeting SARS-CoV-2: a systematic drug repurposing approach to identify promising inhibitors against 3C-like proteinase and 2′-O-ribose methyltransferase
The recent pandemic associated with SARS-CoV-2, a virus of the Coronaviridae family, has
resulted in an unprecedented number of infected people. The highly contagious nature of …
resulted in an unprecedented number of infected people. The highly contagious nature of …
[HTML][HTML] Contriving multi-epitope subunit of vaccine for COVID-19: immunoinformatics approaches
R Dong, Z Chu, F Yu, Y Zha - Frontiers in immunology, 2020 - frontiersin.org
COVID-19 has recently become the most serious threat to public health, and its prevalence
has been increasing at an alarming rate. The incubation period for the virus is~ 1–14 days …
has been increasing at an alarming rate. The incubation period for the virus is~ 1–14 days …
GalaxyRefine: Protein structure refinement driven by side-chain repacking
The quality of model structures generated by contemporary protein structure prediction
methods strongly depends on the degree of similarity between the target and available …
methods strongly depends on the degree of similarity between the target and available …
[HTML][HTML] Structural insight into the role of novel SARS-CoV-2 E protein: A potential target for vaccine development and other therapeutic strategies
The outbreak of COVID-19 across the world has posed unprecedented and global
challenges on multiple fronts. Most of the vaccine and drug development has focused on the …
challenges on multiple fronts. Most of the vaccine and drug development has focused on the …
Designing multi-epitope vaccine against Staphylococcus aureus by employing subtractive proteomics, reverse vaccinology and immuno-informatics approaches
Staphylococcus aureus is a deadly human bacterial pathogen that causes a wide variety of
clinical manifestations. Invasive S. aureus infections in hospitals and the community are one …
clinical manifestations. Invasive S. aureus infections in hospitals and the community are one …
Designing of a multi-epitope vaccine against the structural proteins of marburg virus exploiting the immunoinformatics approach
Marburg virus disease (MVD) caused by the Marburg virus (MARV) generally appears with
flu-like symptoms and leads to severe hemorrhagic fever. It spreads via direct contact with …
flu-like symptoms and leads to severe hemorrhagic fever. It spreads via direct contact with …
[HTML][HTML] Peptide-based vaccines for tuberculosis
W Gong, C Pan, P Cheng, J Wang, G Zhao… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …
GalaxyPepDock: a protein–peptide docking tool based on interaction similarity and energy optimization
Protein–peptide interactions are involved in a wide range of biological processes and are
attractive targets for therapeutic purposes because of their small interfaces. Therefore …
attractive targets for therapeutic purposes because of their small interfaces. Therefore …