Abstract Angiotensin-converting enzyme (ACE)—a zinc-dependent dicarboxypeptidase with
two catalytic domains—plays a major part in blood pressure regulation by converting …

Angiotensin-converting enzyme 2 (ACE2) is related to ACE but turned out to counteract
several pathophysiological actions of ACE. ACE2 exerts antihypertensive and …

Alzheimer's disease is an irreversible, progressive neurodegenerative disorder. Various
therapeutic approaches are being used to improve the cholinergic neurotransmission, but …

In the RAS (renin–angiotensin system), Ang I (angiotensin I) is cleaved by ACE (angiotensin-
converting enzyme) to form Ang II (angiotensin II), which has effects on blood pressure, fluid …

Metallopeptidases form the most diverse of the catalytic types of peptidases, about 30
families being recognized by our criteria (see [i], Volume 244, this series, for definitions of …

Angiotensin-converting enzyme (ACE) is a zinc-dependent peptidase responsible for
converting angiotensin I into the vasoconstrictor angiotensin II. However, ACE is a relatively …

Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the
structure, function, and motion of proteins for students, faculty, and researchers at all levels …

Overlapping genomic clones containing the entire sequence of the human angiotensin I-
converting enzyme (ACE) gene were isolated from a lamda phage human DNA library. This …

Angiotensin converting enzyme (ACE) is well-known for its role in blood pressure regulation
via the renin–angiotensin aldosterone system (RAAS) but also functions in fertility, immunity …

Angiotensin-I-converting enzyme (ACE) is a monomeric, membrane-bound, zinc-and
chloride-dependent peptidyl dipeptidase that catalyzes the conversion of the decapeptide …