Molecular mechanisms and future implications of VEGF/VEGFR in cancer therapy
Angiogenesis, the sprouting of new blood vessels from existing vessels, is one of six known
mechanisms employed by solid tumors to recruit blood vessels necessary for their initiation …
mechanisms employed by solid tumors to recruit blood vessels necessary for their initiation …
[HTML][HTML] The role of VEGF in cancer-induced angiogenesis and research progress of drugs targeting VEGF
S Ghalehbandi, J Yuzugulen, MZI Pranjol… - European Journal of …, 2023 - Elsevier
Angiogenesis is a double-edged sword; it is a mechanism that defines the boundary
between health and disease. In spite of its central role in physiological homeostasis, it …
between health and disease. In spite of its central role in physiological homeostasis, it …
[HTML][HTML] Brown-fat-mediated tumour suppression by cold-altered global metabolism
T Seki, Y Yang, X Sun, S Lim, S Xie, Z Guo, W Xiong… - Nature, 2022 - nature.com
Glucose uptake is essential for cancer glycolysis and is involved in non-shivering
thermogenesis of adipose tissues,,,,–. Most cancers use glycolysis to harness energy for …
thermogenesis of adipose tissues,,,,–. Most cancers use glycolysis to harness energy for …
A concise review of VEGF, PDGF, FGF, Notch, angiopoietin, and HGF signalling in tumor angiogenesis with a focus on alternative approaches and future directions
S Vimalraj - International Journal of Biological Macromolecules, 2022 - Elsevier
Angiogenesis forms new vessels from existing ones. Abnormal angiogenesis, which is what
gives tumor microenvironments their distinctive features, is characterised by convoluted …
gives tumor microenvironments their distinctive features, is characterised by convoluted …
Brain‐targeted HFn‐Cu‐rego nanoplatform for site‐specific delivery and manipulation of autophagy and cuproptosis in glioblastoma
W Jia, H Tian, J Jiang, L Zhou, L Li, M Luo, N Ding… - Small, 2023 - Wiley Online Library
Durable glioblastoma multiforme (GBM) management requires long‐term chemotherapy
after surgery to eliminate remaining cancerous tissues. Among chemotherapeutics …
after surgery to eliminate remaining cancerous tissues. Among chemotherapeutics …
Targeting angiogenesis in breast cancer: current evidence and future perspectives of novel anti-angiogenic approaches
NM Ayoub, SK Jaradat, KM Al-Shami… - Frontiers in …, 2022 - frontiersin.org
Angiogenesis is a vital process for the growth and dissemination of solid cancers. Numerous
molecular pathways are known to drive angiogenic switch in cancer cells promoting the …
molecular pathways are known to drive angiogenic switch in cancer cells promoting the …
Novel drugs with high efficacy against tumor angiogenesis
S Qi, S Deng, Z Lian, K Yu - International Journal of Molecular Sciences, 2022 - mdpi.com
Angiogenesis is involved in physiological and pathological processes in the body. Tumor
angiogenesis is a key factor associated with tumor growth, progression, and metastasis …
angiogenesis is a key factor associated with tumor growth, progression, and metastasis …
Periplocin suppresses the growth of colorectal cancer cells by triggering LGALS3 (galectin 3)-mediated lysophagy
K Wang, S Fu, L Dong, D Zhang, M Wang, X Wu… - Autophagy, 2023 - Taylor & Francis
Colorectal cancer (CRC) is one of the most common malignancies worldwide and remains a
major clinical challenge. Periplocin, a major bioactive component of the traditional Chinese …
major clinical challenge. Periplocin, a major bioactive component of the traditional Chinese …
Bacterial‐Mediated Tumor Therapy: Old Treatment in a New Context
Y Liu, L Niu, N Li, Y Wang, M Liu, X Su, X Bao… - Advanced …, 2023 - Wiley Online Library
Targeted therapy and immunotherapy have brought hopes for precision cancer treatment.
However, complex physiological barriers and tumor immunosuppression result in poor …
However, complex physiological barriers and tumor immunosuppression result in poor …
Fibroblast growth factor receptor signalling dysregulation and targeting in breast cancer
C Francavilla, CS O'Brien - Open Biology, 2022 - royalsocietypublishing.org
Fibroblast Growth Factor Receptor (FGFR) signalling plays a critical role in breast embryonal
development, tissue homeostasis, tumorigenesis and metastasis. FGFR, its numerous FGF …
development, tissue homeostasis, tumorigenesis and metastasis. FGFR, its numerous FGF …