Treatment of knee meniscus pathology: rehabilitation, surgery, and orthobiologics

PS Chirichella, S Jow, S Iacono, HE Wey, GA Malanga - PM&R, 2019 - Wiley Online Library
The meniscal tear treatment paradigm traditionally begins with conservative measures such
as physical therapy and referral for operative management for persistent or mechanical …

Cartilage regeneration by chondrogenic induced adult stem cells in osteoarthritic sheep model

CC Ude, SB Sulaiman, N Min-Hwei, C Hui-Cheng… - PLoS …, 2014 - journals.plos.org
Objectives In this study, Adipose stem cells (ADSC) and bone marrow stem cells (BMSC),
multipotent adult cells with the potentials for cartilage regenerations were induced to …

Reconstruction of limbal stem cell deficient corneal surface with induced human bone marrow mesenchymal stem cells on amniotic membrane

CM Rohaina, KY Then, AMH Ng, WHWA Halim… - Translational …, 2014 - Elsevier
The cornea can be damaged by a variety of clinical disorders or chemical, mechanical, and
thermal injuries. The objectives of this study were to induce bone marrow mesenchymal …

Augmentation of chronic rotator cuff healing using adipose‐derived stem cell‐seeded human tendon‐derived hydrogel

Y Kaizawa, A Franklin, J Leyden… - Journal of …, 2019 - Wiley Online Library
Rotator cuff (RTC) repair outcomes are unsatisfactory due to the poor healing capacity of the
tendon bone interface (TBI). In our preceding study, tendon hydrogel (tHG), which is a type I …

Micro-computed tomography detection of gold nanoparticle-labelled mesenchymal stem cells in the rat subretinal layer

PL Mok, SN Leow, AEH Koh, HH Mohd Nizam… - International journal of …, 2017 - mdpi.com
Mesenchymal stem cells are widely used in many pre-clinical and clinical settings. Despite
advances in molecular technology; the migration and homing activities of these cells in in …

Long-term tracking of the osteogenic differentiation of mouse BMSCs by aggregation-induced emission nanoparticles

M Gao, J Chen, G Lin, S Li, L Wang, A Qin… - … applied materials & …, 2016 - ACS Publications
Bone marrow-derived mesenchymal stem cells (BMSCs) have shown great potential for
bone repair due to their strong proliferation ability and osteogenic capacity. To evaluate and …

The evaluation of cartilage differentiations using transforming growth factor beta3 alone and with combination of bone morphogenetic protein-6 on adult stem cells

CC Ude, HC Chen, MY Norhamdan, BM Azizi… - Cell and Tissue …, 2017 - Springer
In our quest to standardize our formula for a clinical trial, transforming growth factor-beta3
(TGF-β3) alone and in combination with bone morphogenetic protein-6 (BMP-6) were …

Long-term evaluation of osteoarthritis sheep knee, treated with TGF-β3 and BMP-6 induced multipotent stem cells

CC Ude, BS Shamsul, MH Ng, HC Chen… - Experimental …, 2018 - Elsevier
Background Hyaline articular cartilage, which protects the bones of diarthrodial joints from
forces associated with load bearing, frictions, and impacts has very limited capacities for self …

Role of magnesium transporter subtype 1 (MagT1) in the osteogenic differentiation of rat bone marrow stem cells

J Zheng, X Mao, J Ling, C Chen, W Zhang - Biological trace element …, 2016 - Springer
In the present study, we investigated the role of magnesium transporter subtype 1 (MagT1),
a selective Mg transporter protein, in the osteogenic differentiation of rat bone marrow stem …

In vivo bone regeneration on titanium devices using serum‐free grown adipose‐derived stem cells, in a sheep femur model

D Godoy Zanicotti, DE Coates… - Clinical oral implants …, 2017 - Wiley Online Library
Aim The aim of this study was to investigate the capacity of adipose‐derived stem cells
(ADSC), grown in serum‐free conditions, to regenerate bone around titanium discs with …