The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

[HTML][HTML] Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …

[HTML][HTML] Emotional dysregulation in children and adolescents with psychiatric disorders. A narrative review

FW Paulus, S Ohmann, E Möhler, P Plener… - Frontiers in …, 2021 - frontiersin.org
Background: Emotional dysregulation (ED) is a transdiagnostic construct defined as the
inability to regulate the intensity and quality of emotions (such as, fear, anger, sadness), in …

[HTML][HTML] Treatment of posttraumatic stress disorder: a state-of-the-art review

L Burback, S Brémault-Phillips, MJ Nijdam… - Current …, 2024 - ncbi.nlm.nih.gov
This narrative state-of-the-art review paper describes the progress in the understanding and
treatment of Posttraumatic Stress Disorder (PTSD). Over the last four decades, the scientific …

[HTML][HTML] Social brain, social dysfunction and social withdrawal

S Porcelli, N Van Der Wee, S van der Werff… - Neuroscience & …, 2019 - Elsevier
The human social brain is complex. Current knowledge fails to define the neurobiological
processes underlying social behaviour involving the (patho-) physiological mechanisms that …

The social salience hypothesis of oxytocin

SG Shamay-Tsoory, A Abu-Akel - Biological psychiatry, 2016 - Elsevier
Oxytocin is a nonapeptide that also serves as a neuromodulator in the human central
nervous system. Over the last decade, a sizeable body of literature has examined its effects …

Vasopressin and oxytocin receptor systems in the brain: sex differences and sex-specific regulation of social behavior

KM Dumais, AH Veenema - Frontiers in neuroendocrinology, 2016 - Elsevier
The neuropeptides vasopressin (VP) and oxytocin (OT) and their receptors in the brain are
involved in the regulation of various social behaviors and have emerged as drug targets for …

Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine

A Meyer-Lindenberg, G Domes, P Kirsch… - Nature Reviews …, 2011 - nature.com
The neuropeptides oxytocin (OXT) and arginine vasopressin (AVP) are evolutionarily highly
conserved mediators in the regulation of complex social cognition and behaviour. Recent …

[HTML][HTML] The role of oxytocin in social bonding, stress regulation and mental health: an update on the moderating effects of context and interindividual differences

M Olff, JL Frijling, LD Kubzansky, B Bradley… - …, 2013 - Elsevier
In this review we summarize the results and conclusions of five studies as presented in a
symposium at the 42nd annual meeting of the International Society for …

Psychobiological mechanisms underlying the social buffering of the hypothalamic–pituitary–adrenocortical axis: A review of animal models and human studies across …

CE Hostinar, RM Sullivan, MR Gunnar - Psychological bulletin, 2014 - psycnet.apa.org
Discovering the stress-buffering effects of social relationships has been one of the major
findings in psychobiology in the last century. However, an understanding of the underlying …