High-resolution studies of lysis–lysogeny decision-making in bacteriophage lambda
Cellular decision-making guides complex development such as cell differentiation and
disease progression. Much of our knowledge about decision-making is derived from simple …
disease progression. Much of our knowledge about decision-making is derived from simple …
Single-cell studies of phage λ: hidden treasures under Occam's rug
I Golding - Annual Review of Virology, 2016 - annualreviews.org
Studies over more than half a century have resulted in what some consider a complete
narrative for the life cycle of bacteriophage λ. However, this narrative is only complete within …
narrative for the life cycle of bacteriophage λ. However, this narrative is only complete within …
Using bacterial population dynamics to count phages and their lysogens
Traditional assays for counting bacteriophages and their lysogens are labor-intensive and
perturbative to the host cells. Here, we present a high-throughput infection method in a …
perturbative to the host cells. Here, we present a high-throughput infection method in a …
Temperature-induced DNA density transition in phage λ capsid revealed with contrast-matching SANS
JR Villanueva Valencia, E Tsimtsirakis… - Proceedings of the …, 2023 - National Acad Sciences
Structural details of a genome packaged in a viral capsid are essential for understanding
how the structural arrangement of a viral genome in a capsid controls its release dynamics …
how the structural arrangement of a viral genome in a capsid controls its release dynamics …
CRP represses the CRISPR/Cas system in Escherichia coli: evidence that endogenous CRISPR spacers impede phage P1 replication
The CRISPR/Cas system is an important aspect in bacterial immunology. The anti‐phage
activity of the CRISPR system has been established using synthetic CRISPR spacers, but in …
activity of the CRISPR system has been established using synthetic CRISPR spacers, but in …
Bacteriophages from ExPEC reservoirs kill pandemic multidrug-resistant strains of clonal group ST131 in animal models of bacteremia
Multi-drug resistant (MDR) enteric bacteria are of increasing global concern. A clonal group,
Escherichia coli sequence type (ST) 131, harbors both MDR and a deadly complement of …
Escherichia coli sequence type (ST) 131, harbors both MDR and a deadly complement of …
Stable-isotope probing and metagenomics reveal predation by protozoa drives E. coli removal in slow sand filters
Stable-isotope probing and metagenomics were applied to study samples taken from
laboratory-scale slow sand filters 0.5, 1, 2, 3 and 4 h after challenging with 13C-labelled …
laboratory-scale slow sand filters 0.5, 1, 2, 3 and 4 h after challenging with 13C-labelled …
K5 Capsule and Lipopolysaccharide Are Important in Resistance to T4 Phage Attack in Probiotic E. coli Strain Nissle 1917
M Soundararajan, R von Bünau… - Frontiers in …, 2019 - frontiersin.org
Rapidly growing antibiotic resistance among gastrointestinal pathogens, and the ability of
antibiotics to induce the virulence of these pathogens makes it increasingly difficult to rely on …
antibiotics to induce the virulence of these pathogens makes it increasingly difficult to rely on …
Coinfecting phages impede each other's entry into the cell
The developmental choice made by temperate phages, between cell death (lysis) and viral
dormancy (lysogeny), is influenced by the relative abundance of viruses and hosts in the …
dormancy (lysogeny), is influenced by the relative abundance of viruses and hosts in the …
Lysis‐lysogeny coexistence: prophage integration during lytic development
The infection of Escherichia coli cells by bacteriophage lambda results in bifurcated means
of propagation, where the phage decides between the lytic and lysogenic pathways …
of propagation, where the phage decides between the lytic and lysogenic pathways …