[HTML][HTML] Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome

R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …

Obstructive sleep apnea: current perspectives

AM Osman, SG Carter, JC Carberry… - Nature and science of …, 2018 - Taylor & Francis
The prevalence of obstructive sleep apnea (OSA) continues to rise. So too do the health,
safety, and economic consequences. On an individual level, the causes and consequences …

Phenotypic approaches to obstructive sleep apnoea–new pathways for targeted therapy

DJ Eckert - Sleep medicine reviews, 2018 - Elsevier
People develop obstructive sleep apnoea (OSA) for different reasons. The ability to
understand these reasons, easily identify them in individual patients, and develop therapies …

Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets

DJ Eckert, DP White, AS Jordan, A Malhotra… - American journal of …, 2013 - atsjournals.org
Rationale: The pathophysiologic causes of obstructive sleep apnea (OSA) likely vary among
patients but have not been well characterized. Objectives: To define carefully the proportion …

International consensus statement on obstructive sleep apnea

JL Chang, AN Goldberg, JA Alt… - International forum of …, 2023 - Wiley Online Library
Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …

Phenotypic subtypes of OSA: a challenge and opportunity for precision medicine

A Zinchuk, HK Yaggi - Chest, 2020 - Elsevier
Current strategies for the management of OSA reflect a one-size-fits-all approach. Diagnosis
and severity of OSA are based on the apnea-hypopnea index and treatment initiated with …

Phenotyping pharyngeal pathophysiology using polysomnography in patients with obstructive sleep apnea

SA Sands, BA Edwards, PI Terrill… - American journal of …, 2018 - atsjournals.org
Rationale: Therapies for obstructive sleep apnea (OSA) could be administered on the basis
of a patient's own phenotypic causes (“traits”) if a clinically applicable approach were …

[图书][B] Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: the evidence report

National Heart, Lung, Blood Institute… - 1998 - books.google.com
Page 1 Obesity Education Initiative TAUB RA 11 .B15 A25127 no.984083 D PRESSURE
tivation LAORTALITY OVERWEIGHT BODY MASS INDEX prevalence BEHAVIOR DIETARY …

Obesity and obstructive sleep apnea: pathogenic mechanisms and therapeutic approaches

AR Schwartz, SP Patil, AM Laffan… - Proceedings of the …, 2008 - atsjournals.org
Obstructive sleep apnea is a common disorder whose prevalence is linked to an epidemic of
obesity in Western society. Sleep apnea is due to recurrent episodes of upper airway …

Role of nocturnal rostral fluid shift in the pathogenesis of obstructive and central sleep apnoea

LH White, TD Bradley - The Journal of physiology, 2013 - Wiley Online Library
Obstructive sleep apnoea (OSA) is common in the general population and increases the risk
of motor vehicle accidents due to hypersomnolence from sleep disruption, and risk of …