The role of interleukin‐6 in monitoring severe case of coronavirus disease 2019

T Liu, J Zhang, Y Yang, H Ma, Z Li, J Zhang… - EMBO molecular …, 2020 - embopress.org
Progression to severe disease is a difficult problem in treating coronavirus disease 2019
(COVID‐19). The purpose of this study is to explore changes in markers of severe disease in …

IL-6 and IL-10 as predictors of disease severity in COVID-19 patients: results from meta-analysis and regression

SK Dhar, K Vishnupriyan, S Damodar, S Gujar, M Das - Heliyon, 2021 - cell.com
Abstract Aims SARS-CoV-2, an infectious agent behind the ongoing COVID-19 pandemic,
induces high levels of cytokines such as IL-1, IL-2, IL-4, IL-6, IL-10, TNF-α, IFN-γ etc in …

The potential role of IL-6 in monitoring severe case of coronavirus disease 2019

T Liu, J Zhang, Y Yang, H Ma, Z Li, J Zhang, J Cheng… - MedRxiv, 2020 - medrxiv.org
Background The outbreak of coronavirus disease 2019 (COVID-19) in Wuhan City, China
has spreads rapidly since December, 2019. Most patients show mild symptoms, but some of …

Host inflammatory biomarkers of disease severity in pediatric community-acquired pneumonia: a systematic review and meta-analysis

CD Fernandes, MB Arriaga, MCM Costa… - Open Forum …, 2019 - academic.oup.com
Background Community-acquired pneumonia (CAP) is the leading cause of death in
children. Identification of reliable biomarkers offers the potential to develop a severity …

Proteomic blood profiling in mild, severe and critical COVID-19 patients

H Patel, NJ Ashton, RJB Dobson, LM Andersson… - Scientific reports, 2021 - nature.com
The recent SARS-CoV-2 pandemic manifests itself as a mild respiratory tract infection in
most individuals, leading to COVID-19 disease. However, in some infected individuals, this …

Potential immunotherapeutic targets for hypoxia due to COVI-Flu

Y Leyfman, TK Erick, SS Reddy, S Galwankar… - Shock, 2020 - journals.lww.com
The world is currently embroiled in a pandemic of coronavirus disease 2019 (COVID-19), a
respiratory illness caused by the novel betacoronavirus severe acute respiratory syndrome …

Efficacy of convalescent plasma therapy compared to fresh frozen plasma in severely ill COVID-19 patients: a pilot randomized controlled trial

M Bajpai, S Kumar, A Maheshwari, K Chhabra, P kale… - MedRxiv, 2020 - medrxiv.org
Background The role of convalescent plasma (COPLA) for the treatment of severely ill
Corona Virus Disease-2019 is under investigation. We compared the efficacy and safety of …

Interleukin-6 and C-reactive protein/albumin ratio as predictors of COVID-19 severity and mortality

M El-Shabrawy, ME Alsadik, M El-Shafei… - The Egyptian Journal of …, 2021 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) was announced in early
December 2019. The pandemic situation is declared. This study aimed to evaluate the role …

Identification of robust protein associations with COVID-19 disease based on five clinical studies

K Suhre, H Sarwath, R Engelke, MU Sohail… - Frontiers in …, 2022 - frontiersin.org
Multiple studies have investigated the role of blood circulating proteins in COVID-19 disease
using the Olink affinity proteomics platform. However, study inclusion criteria and sample …

[HTML][HTML] Role of tumor necrosis factor-α in the mortality of hospitalized patients with severe and critical COVID-19 pneumonia

F Jia, G Wang, J Xu, J Long, F Deng, W Jiang - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Abstract The coronavirus disease 2019 (COVID-19) is presently the most pressing public
health concern worldwide. Cytokine storm is an important factor leading to death of patients …