Chemometrics-Assisted UV-Vis Spectrophotometry for Quality Control of Pharmaceuticals: A Review

LH Nurani, CA Edityaningrum, I Irnawati… - Indonesian Journal of …, 2023 - journal.ugm.ac.id
Spectroscopic method in the UV-Vis region is considered the most molecular spectrometric
method for content determination of a single component. However, a lot of pharmaceutical …

Application of multivariate chemometrics tools for spectrophotometric determination of naphazoline HCl, pheniramine maleate and three official impurities in their eye …

KM Kelani, MA Hegazy, AM Hassan, MA Tantawy - Scientific Reports, 2023 - nature.com
This work is concerned with exploiting the power of chemometrics in the assay and purity
determination of naphazoline HCl (NZ) and pheniramine maleate (PN) in their combined …

A green TLC densitometric method for the simultaneous detection and quantification of naphazoline HCl, pheniramine maleate along with three official impurities

KM Kelani, MA Hegazy, AM Hassan, MA Tantawy - BMC chemistry, 2022 - Springer
Impurity profiling of a pharmaceutical compound is now taking great attention during quality
assessment of pharmaceuticals, as presence of small amount of impurities may affect safety …

A sustainable data processing approach using ultraviolet-spectroscopy as a powerful spectral resolution tool for simultaneously estimating newly approved eye …

KAM Attia, A El-Olemy, AEF Abbas… - Journal of Chemical …, 2023 - journals.sagepub.com
Drug impurities are now seen as a major threat to drug safety around the world, especially
when it comes to carcinogenic impurities. Here, we present the first spectrophotometric …

The application of artificial intelligence system and regression methods based on the spectrophotometric method for fast simultaneous determination of naphazoline …

Z Shahrokhi, MR Sohrabi, SM Nik - Optik, 2020 - Elsevier
In this study, reliable and quick methods based on ultraviolet-visible spectrophotometry (UV–
Vis) for the simultaneous determination of Naphazoline (NAP) and Antazoline (ANT) were …

Development of a Novel Versatile Method for Determination of two Antihistamines in Association with Naphazoline Using Cathodically Pretreated Boron‐doped …

TC Oliveira, JM Freitas, RAA Muñoz… - Electroanalysis, 2018 - Wiley Online Library
Antihistamines such as pheniramine (PHN) or chlorpheniramine (CPH) are commonly
associated with naphazoline (NPZ) in eye drops and nasal decongestants. In this work, a …

Determination of naphazoline HCl, pheniramine maleate and their official impurities in eye drops and biological fluid rabbit aqueous humor by a validated LC-DAD …

KM Kelani, MA Hegazy, AM Hassan, MA Tantawy - RSC advances, 2021 - pubs.rsc.org
A simple RP-HPLC-DAD method was developed and validated, as per the ICH guidelines,
for simultaneous determination of naphazoline HCl (NPZ) & pheniramine maleate (PHN) …

Development of a novel UPLC approach to co-prediction of four active compounds in a multi-component pharmaceutical preparation

Ö Üstündağ, A Üçer, E Dinç - Journal of Chromatography B, 2024 - Elsevier
In this work, a new ultra-performance liquid chromatography method based on photodiode
array detection (UPLC-PDA) was first developed for the quantitative analysis of the …

[HTML][HTML] Sub-minute method for determination of naphazoline in the presence of diphenhydramine, pheniramine or chlorpheniramine by capillary electrophoresis

MMAC Ribeiro, MC Marra, B Costa… - Journal of the Brazilian …, 2018 - SciELO Brasil
This paper presents a simple and low-cost capillary electrophoresis method for ultra-fast
simultaneous determination of naphazoline (NPZ) and one of the following active …

Simultaneous determination of paracetamol, dextromethorphan, chlorpheniramine, pseudoephedrine and major impurities of paracetamol and pseudoephedrine by …

B Yener, C Erkmen, B Uslu, NG Goger - Brazilian Journal of …, 2022 - SciELO Brasil
A capillary electrophoresis method was developed for the first time and optimized for the
determination of paracetamol, pseudoephedrine, dextromethorphan, chlorpheniramine, 4 …