Abstract Ischemia-reperfusion (I/R) injury paradoxically occurs during reperfusion following
ischemia, exacerbating the initial tissue damage. The limited understanding of the intricate …

Cartilage not only plays essential roles in skeletal development and growth during pre-and
postnatal stages but also serves to provide smooth movement of skeletons throughout life …

Adult articular chondrocytes undergo slow senescence and dedifferentiation during in vitro
expansion, restricting successful cartilage regeneration. A complete understanding of the …

Objective—In calcific aortic valve disease, myofibroblasts and activation of the transforming
growth factor-β1 (TGF-β1) and Wnt/β-catenin pathways are observed in the fibrosa, the stiffer …

The transcription factor c‐Myc is a key regulator of cell proliferation, cell growth,
differentiation, and apoptosis. Deregulated c‐myc expression possesses a high …

Purpose Apoptosis is an important physiological process, making a great difference to
development and tissue homeostasis. Osteoarthritis (OA) is a chronic joint disease …

Regenerating chondral and osteochondral injuries is a main challenge in orthopedics.
Some therapeutic strategies such as joint preservation operations, non-operative …

Osteoarthritis (OA) is the most common chronic joint disorder worldwide, with a high
personal burden for the patients and an important socio-economic impact. Current therapies …

Cervical cancer is the major cause of cancer related deaths in women, especially in
developing countries and Human Papilloma Virus infection in conjunction with multiple …

Introduction The effect of low-intensity pulsed ultrasound (LIPUS) on cell growth was
examined in three-dimensional-cultured chondrocytes with a collagen sponge. To elucidate …