Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) family in physiological and pathophysiological process and diseases
L Qian, Y Zhu, C Deng, Z Liang, J Chen… - … and Targeted Therapy, 2024 - nature.com
Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) family (PGC-1s),
consisting of three members encompassing PGC-1α, PGC-1β, and PGC-1-related …
consisting of three members encompassing PGC-1α, PGC-1β, and PGC-1-related …
PGC-1 coactivators: shepherding the mitochondrial biogenesis of tumors
C Luo, HR Widlund, P Puigserver - Trends in cancer, 2016 - cell.com
As coordinators of energy demands and nutritional supplies, the peroxisome proliferator-
activated receptor γ (PPARγ) coactivator 1 (PGC-1) family of transcriptional coactivators …
activated receptor γ (PPARγ) coactivator 1 (PGC-1) family of transcriptional coactivators …
Role of HIF-1α/ERRα in enhancing cancer cell metabolism and promoting resistance of endometrial cancer cells to pyroptosis
P Su, L Yu, X Mao, P Sun - Frontiers in Oncology, 2022 - frontiersin.org
Oxygen is critical to energy metabolism, and tumors are often characterized by a hypoxic
microenvironment. Owing to the high metabolic energy demand of malignant tumor cells …
microenvironment. Owing to the high metabolic energy demand of malignant tumor cells …
miR‐22‐3p/PGC1β Suppresses Breast Cancer Cell Tumorigenesis via PPARγ
X Wang, Z Yao, L Fang - PPAR research, 2021 - Wiley Online Library
In this study, we found that miR‐22‐3p expression was decreased in breast cancer (BC) cell
lines and tissues. Overexpression of miR‐22‐3p inhibited the proliferation and migration of …
lines and tissues. Overexpression of miR‐22‐3p inhibited the proliferation and migration of …
PGC-1β and ERRα promote glutamine metabolism and colorectal cancer survival via transcriptional upregulation of PCK2
Simple Summary Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 Beta
(PGC-1β) and Estrogen-Related Receptor Alpha (ERRα) are proteins that are over …
(PGC-1β) and Estrogen-Related Receptor Alpha (ERRα) are proteins that are over …
Pan-cancer analysis reveals PPRC1 as a novel prognostic biomarker in ovarian cancer and hepatocellular carcinoma
X Ruan, G Cui, C Li, Z Sun - Medicina, 2023 - mdpi.com
Background and Objectives: As is well understood, peroxisome proliferator-activated
receptor gamma cofactor-related 1 (PPRC1) plays a central role in the transcriptional control …
receptor gamma cofactor-related 1 (PPRC1) plays a central role in the transcriptional control …
PGC-1β cooperating with FOXA2 inhibits proliferation and migration of breast cancer cells
J Cao, X Wang, D Wang, R Ma, X Li, H Feng… - Cancer Cell …, 2019 - Springer
Background Breast cancer is one of the most common malignancy among females from the
worldwide cancer incidence statistics. Peroxisome gamma coactivator-1β (PGC-1β) has …
worldwide cancer incidence statistics. Peroxisome gamma coactivator-1β (PGC-1β) has …
[HTML][HTML] Systemic lipid peroxidation profile from patients with breast cancer changes according to the lymph nodal metastasis status
ST de Oliveira, MP Bessani, TB Scandolara… - …, 2022 - ncbi.nlm.nih.gov
Metastasis is the leading cause of cancer death. Considering that lymph nodes are the
major pathway for cancer spreading and that the metastatic process is under oxidative stress …
major pathway for cancer spreading and that the metastatic process is under oxidative stress …
Banana green peels extract protects against nonalcoholic fatty liver disease in high‐fat‐fed mice through modulation of lipid metabolism and inflammation
WA Barroso, MB Serra, IC Abreu… - Phytotherapy …, 2022 - Wiley Online Library
We investigate the effect of the banana green peels extract (BPE) as a preventive treatment
against NAFLD in high‐fat diet fed mice. Mice received daily doses of 100 or 250 mg/kg of …
against NAFLD in high‐fat diet fed mice. Mice received daily doses of 100 or 250 mg/kg of …
An integrated bioinformatic investigation of mitochondrial energy metabolism genes in colon adenocarcinoma followed by preliminary validation of CPT2 in tumor …
Z Cao, J Lin, G Fu, L Niu, Z Yang, W Cai - Frontiers in Immunology, 2022 - frontiersin.org
Background The prognosis for colon adenocarcinoma (COAD) today remains poor.
Changes in mitochondria-related genes and metabolic reprogramming are related to tumor …
Changes in mitochondria-related genes and metabolic reprogramming are related to tumor …