3′-untranslated regions (3′-UTRs) are the noncoding parts of mRNAs. Compared to
yeast, in humans, median 3′-UTR length has expanded approximately tenfold alongside …

From transcription, to transport, storage, and translation, RNA depends on association with
different RNA‐binding proteins (RBPs). Methods based on next‐generation sequencing and …

HuR/ELAVL1 is an RNA-binding protein involved in differentiation and stress response that
acts primarily by stabilizing messenger RNA (mRNA) targets. HuR comprises three RNA …

Abstract The Human antigen R (HuR) protein is an RNA-binding protein, ubiquitously
expressed in human tissues, that orchestrates target RNA maturation and processing both in …

Lung cancer (LC) is often diagnosed at an advanced stage and conventional treatments for
disease management have limitations associated with them. Novel therapeutic targets are …

Human antigen R (HuR) is a 32 kDa protein with 3 RNA Recognition Motifs (RRMs), which
bind to Adenylate and uridylate Rich Elements (AREs) of mRNAs. Whereas the N-terminal …

Ionizing radiation may be of both artificial and natural origin and causes cellular damage in
living organisms. Radioactive isotopes have been used significantly in cancer therapy for …

Cytokines and growth factors regulate cell proliferation, differentiation, migration and
apoptosis, and play important roles in coordinating growth signal responses during …

Hu-antigen R (HuR) is an RNA-binding posttranscriptional regulator that belongs to the
Hu/ELAV family. HuR expression levels are modulated by a variety of proteins, microRNAs …

The RNA binding protein Human antigen R (HuR) interacts with specific AU-rich domains in
target mRNAs and is highly expressed in many cell types, including cardiomyocytes …