Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

SS Patel, A Acharya, RS Ray, R Agrawal… - Critical reviews in …, 2020 - Taylor & Francis
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …

Cholinergic system and its therapeutic importance in inflammation and autoimmunity

N Halder, G Lal - Frontiers in immunology, 2021 - frontiersin.org
Neurological and immunological signals constitute an extensive regulatory network in our
body that maintains physiology and homeostasis. The cholinergic system plays a significant …

Curcumin and diabetes: a systematic review

D Zhang, M Fu, SH Gao, JL Liu - … ‐Based Complementary and …, 2013 - Wiley Online Library
Turmeric (Curcuma longa), a rhizomatous herbaceous perennial plant of the ginger family,
has been used for the treatment of diabetes in Ayurvedic and traditional Chinese medicine …

Therapeutic potential of curcumin in diabetic complications

N Parsamanesh, M Moossavi, A Bahrami… - Pharmacological …, 2018 - Elsevier
Diabetes mellitus is an extremely prevalent endocrine disease and a major global public
health concern. Diabetic complications, such as retinopathy, nephropathy, neuropathy and …

Examining the potential clinical value of curcumin in the prevention and diagnosis of Alzheimer's disease

KG Goozee, TM Shah, HR Sohrabi… - British Journal of …, 2016 - cambridge.org
Curcumin derived from turmeric is well documented for its anti-carcinogenic, antioxidant and
anti-inflammatory properties. Recent studies show that curcumin also possesses …

Antioxidant and antiinflammatory activities of curcumin on diabetes mellitus and its complications

B Meng, J Li, H Cao - Current pharmaceutical design, 2013 - ingentaconnect.com
Diabetes mellitus (DM) has reached pandemic status and shows no signs of abatement. It
can severely impair people's quality of life and affects patients all over the world. Since it is a …

Neuroprotective effect of ginger in the brain of streptozotocin-induced diabetic rats

G El-Akabawy, W El-Kholy - Annals of anatomy-Anatomischer anzeiger, 2014 - Elsevier
Diabetes mellitus results in neuronal damage caused by increased intracellular glucose
leading to oxidative stress. Recent evidence revealed the potential of ginger for reducing …

A novel curcumin derivative for the treatment of diabetic neuropathy

DJ Daugherty, A Marquez, NA Calcutt, D Schubert - Neuropharmacology, 2018 - Elsevier
Neuropathy is a common complication of long-term diabetes. Proposed mechanisms of
neuronal damage caused by diabetes that are downstream of hyperglycemia and/or loss of …

Curcuminoids in neurodegenerative diseases

D SHL Kim, JY Kim, Y Han - Recent Patents on CNS Drug …, 2012 - ingentaconnect.com
Neurodegeneration is a term used to describe progressive deterioration of structure and/or
function of neurons that affects different parts of the central nervous system and leads to …

Improvement of brain energy metabolism and cholinergic functions contributes to the beneficial effects of silibinin against streptozotocin induced memory impairment

S Tota, PK Kamat, R Shukla, C Nath - Behavioural brain research, 2011 - Elsevier
Recently, silibinin, a clinically used hepatoprotectant, has been reported to prevent amyloid
beta induced memory impairment by reducing oxidative stress and inflammation in mice …