MiRNA biomarkers in cancers of the male reproductive system: are we approaching clinical application?
V Constâncio, NT Tavares, R Henrique… - …, 2023 - Wiley Online Library
Background Specific cancer types face specific clinical management challenges. Owing to
their stability, robustness and fast, easy and cost‐effective detection, microRNAs (miRNAs) …
their stability, robustness and fast, easy and cost‐effective detection, microRNAs (miRNAs) …
Biomarkers for the Detection and Risk Stratification of Aggressive Prostate Cancer
S Eickelschulte, AL Riediger, AK Angeles, F Janke… - Cancers, 2022 - mdpi.com
Simple Summary Prostate cancer is a heterogeneous disease and a major cause of cancer
deaths worldwide. The most widely used prostate cancer biomarker, prostate-specific …
deaths worldwide. The most widely used prostate cancer biomarker, prostate-specific …
Increased miR‐34c mediates synaptic deficits by targeting synaptotagmin 1 through ROS‐JNK‐p53 pathway in Alzheimer's disease
Z Shi, K Zhang, H Zhou, L Jiang, B Xie, R Wang… - Aging cell, 2020 - Wiley Online Library
Alzheimer's disease (AD) and cancer have inverse relationship in many aspects. Some
tumor suppressors, including miR‐34c, are decreased in cancer but increased in AD. The …
tumor suppressors, including miR‐34c, are decreased in cancer but increased in AD. The …
A five‐microRNA model (pCaP) for predicting prostate cancer aggressiveness using cell‐free urine
J Fredsøe, AKI Rasmussen, P Mouritzen… - … journal of cancer, 2019 - Wiley Online Library
Improved biomarkers for prostate cancer (PC) risk stratification are urgently needed. Here,
we aimed to develop a novel multimarker model for prediction of biochemical recurrence …
we aimed to develop a novel multimarker model for prediction of biochemical recurrence …
miR‐142‐3p modulates cell invasion and migration via PKM2‐mediated aerobic glycolysis in colorectal cancer
JY Ren, W Li, G Pan, F Huang, J Yang… - Analytical cellular …, 2021 - Wiley Online Library
Decreased expression of miR‐142‐3p was observed in human cancers. However, the
function and mechanism of miR‐142‐3p in human colorectal cancer remain obscure. The …
function and mechanism of miR‐142‐3p in human colorectal cancer remain obscure. The …
Novel gene signatures predictive of patient recurrence-free survival and castration resistance in prostate cancer
Simple Summary Molecular signatures predictive of recurrence-free survival (RFS) and
castration resistance are critical for treatment decision-making in prostate cancer (PCa), but …
castration resistance are critical for treatment decision-making in prostate cancer (PCa), but …
Profiling of circulating microRNAs in prostate cancer reveals diagnostic biomarker potential
J Fredsøe, AKI Rasmussen, P Mouritzen, MT Bjerre… - Diagnostics, 2020 - mdpi.com
Early detection of prostate cancer (PC) is paramount as localized disease is generally
curable, while metastatic PC is generally incurable. There is a need for improved, minimally …
curable, while metastatic PC is generally incurable. There is a need for improved, minimally …
A novel predictor tool of biochemical recurrence after radical prostatectomy based on a five-microRNA tissue signature
Z Zhao, S Weickmann, M Jung, M Lein, E Kilic… - Cancers, 2019 - mdpi.com
Within five to ten years after radical prostatectomy (RP), approximately 15–34% of prostate
cancer (PCa) patients experience biochemical recurrence (BCR), which is defined as …
cancer (PCa) patients experience biochemical recurrence (BCR), which is defined as …
The potential of microRNAs as non-invasive prostate cancer biomarkers: A systematic literature review based on a machine learning approach
Simple Summary Prostate cancer (PCa) is the most common cancer in men worldwide.
Screening and diagnosis are based on prostate-specific antigen (PSA) blood testing and …
Screening and diagnosis are based on prostate-specific antigen (PSA) blood testing and …
Transcriptomic profiling identifies DCBLD2 as a diagnostic and prognostic biomarker in pancreatic ductal adenocarcinoma
Z Feng, K Li, Y Wu, C Peng - Frontiers in molecular biosciences, 2021 - frontiersin.org
Background: Accumulating evidence shows that the elevated expression of DCBLD2
(discoidin, CUB and LCCL domain-containing protein 2) is associated with unfavorable …
(discoidin, CUB and LCCL domain-containing protein 2) is associated with unfavorable …