The neural and genetic basis of executive function: attention, cognitive flexibility, and response inhibition

SF Logue, TJ Gould - Pharmacology Biochemistry and Behavior, 2014 - Elsevier
Executive function is a collection of cognitive processes essential for higher order mental
function. Processes involved in executive function include, but are not limited to, working …

Serotonin and prefrontal cortex function: neurons, networks, and circuits

MV Puig, AT Gulledge - Molecular neurobiology, 2011 - Springer
Higher-order executive tasks such as learning, working memory, and behavioral flexibility
depend on the prefrontal cortex (PFC), the brain region most elaborated in primates. The …

Multi-target strategies for the improved treatment of depressive states: conceptual foundations and neuronal substrates, drug discovery and therapeutic application

MJ Millan - Pharmacology & therapeutics, 2006 - Elsevier
Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

Serotonin as a modulator of glutamate-and GABA-mediated neurotransmission: implications in physiological functions and in pathology

L Ciranna - Current neuropharmacology, 2006 - ingentaconnect.com
The neurotransmitter serotonin (5-HT), widely distributed in the central nervous system
(CNS), is involved in a large variety of physiological functions. In several brain regions 5-HT …

Selective serotonergic excitation of callosal projection neurons

D Avesar, AT Gulledge - Frontiers in neural circuits, 2012 - frontiersin.org
Serotonin (5-HT) acting as a neurotransmitter in the cerebral cortex is critical for cognitive
function, yet how 5-HT regulates information processing in cortical circuits is not well …

Serotonergic hyperactivity as a potential factor in developmental, acquired and drug-induced synesthesia

B Brogaard - Frontiers in human neuroscience, 2013 - frontiersin.org
Though synesthesia research has seen a huge growth in recent decades, and tremendous
progress has been made in terms of understanding the mechanism and cause of …

GABAB receptor association with the PDZ scaffold Mupp1 alters receptor stability and function

S Balasubramanian, SR Fam, RA Hall - Journal of Biological Chemistry, 2007 - ASBMB
γ-Aminobutyric acid, type B (GABA B) receptors are heterodimeric G protein-coupled
receptors that mediate slow inhibitory synaptic transmission in the central nervous system …

The molecular interaction between the glutamatergic, noradrenergic, dopaminergic and serotoninergic systems informs a detailed genetic perspective on depressive …

A Drago, C Crisafulli, A Sidoti, A Serretti - Progress in neurobiology, 2011 - Elsevier
The glutamatergic pathway has been consistently involved in the physiopathology of
depressive disorder. However a complete dissection and integration of its role in the context …

Serotonergic modulation across sensory modalities

TR Sizemore, LM Hurley… - Journal of …, 2020 - journals.physiology.org
The serotonergic system has been widely studied across animal taxa and different functional
networks. This modulatory system is therefore well positioned to compare the consequences …

Modulation of somatosensory evoked fields from SI and SII by acute GABAA-agonism and paired-pulse stimulation

J Huttunen, E Pekkonen, R Kivisaari, T Autti… - Neuroimage, 2008 - Elsevier
The purpose of the present study was to shed light on the physiology underlying
somatosensory evoked magnetic fields (SEFs) by means of pharmacological manipulation …