[HTML][HTML] Mechanistic insight into diabetic wounds: Pathogenesis, molecular targets and treatment strategies to pace wound healing

S Patel, S Srivastava, MR Singh, D Singh - Biomedicine & …, 2019 - Elsevier
Wound management in diabetic patient is of an extreme clinical and social concern. The
delayed and impaired healing makes it more critical for research focus. The research on …

Re-epithelialization of adult skin wounds: Cellular mechanisms and therapeutic strategies

P Rousselle, F Braye, G Dayan - Advanced Drug Delivery Reviews, 2019 - Elsevier
Cutaneous wound healing in adult mammals is a complex multi-step process involving
overlapping stages of blood clot formation, inflammation, re-epithelialization, granulation …

[HTML][HTML] Phenotypic transitions of macrophages orchestrate tissue repair

ML Novak, TJ Koh - The American journal of pathology, 2013 - Elsevier
Macrophages are essential for the efficient healing of numerous tissues, and they contribute
to impaired healing and fibrosis. Tissue repair proceeds through overlapping phases of …

Tissue engineering of replacement skin: the crossroads of biomaterials, wound healing, embryonic development, stem cells and regeneration

AD Metcalfe, MWJ Ferguson - Journal of the Royal …, 2007 - royalsocietypublishing.org
Advanced therapies combating acute and chronic skin wounds are likely to be brought
about using our knowledge of regenerative medicine coupled with appropriately tissue …

Apparatus for aspirating, irrigating and cleansing wounds

PL Blott, EY Hartwell, D Nicolini, J Lee-Webb - US Patent 8,535,296, 2013 - Google Patents
An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a
conformable wound dressing and wound exudate from the dressing are recirculated by a …

Wound treatment apparatus and method

PL Blott, EY Hartwell, J Lee-Webb, D Nicolini… - US Patent …, 2017 - Google Patents
An apparatus and method for aspirating, irrigating and/or cleansing wounds is provided. The
apparatus and method include one or more of the following: simultaneous aspiration and …

Wound treatment apparatus and method

PL Blott, EY Hartwell, J Lee-Webb, D Nicolini… - US Patent …, 2013 - Google Patents
2011-05-13 Assigned to SMITH & NEPHEW PLC reassignment SMITH & NEPHEW PLC
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …

Concise review: clinical translation of wound healing therapies based on mesenchymal stem cells

WM Jackson, LJ Nesti, RS Tuan - Stem cells translational …, 2012 - academic.oup.com
There is enormous worldwide demand for therapies to promote the efficient resolution of
hard-to-heal wounds with minimal appearance of scarring. Recent in vitro studies with …

Mesenchymal stem cell therapy for attenuation of scar formation during wound healing

WM Jackson, LJ Nesti, RS Tuan - Stem cell research & therapy, 2012 - Springer
Scars are a consequence of cutaneous wound healing that can be both unsightly and
detrimental to the function of the tissue. Scar tissue is generated by excessive deposition of …

Mesenchymal stem cells from adipose tissue in clinical applications for dermatological indications and skin aging

M Gaur, M Dobke, VV Lunyak - International journal of molecular sciences, 2017 - mdpi.com
Operating at multiple levels of control, mesenchymal stem cells from adipose tissue (ADSCs)
communicate with organ systems to adjust immune response, provide signals for …