Over the course of three decades of study, the deubiquitinase Herpesvirus associated
Ubiquitin-Specific Protease/Ubiquitin-Specific Protease 7 (HAUSP/USP7) has gradually …

Ubiquitination is a reversible post-translational modification based on the chemical addition
of ubiquitin to proteins with regulatory effects on various signaling pathways. Ubiquitination …

Tumor development relies on a complex and aberrant tissue environment in which cancer
cells receive the necessary nutrients for growth, survive through immune escape, and …

A biological process called epithelial-mesenchymal transition (EMT) allows epithelial cells to
change into mesenchymal cells and acquire some cancer stem cell properties. EMT …

Recent multi-omics studies, including proteomics, transcriptomics, genomics, and
metabolomics have revealed the critical role of post-translational modifications (PTMs) in the …

Epithelial mesenchymal transition (EMT) is a fundamental and highly regulated process that
is normally observed during embryonic development and tissue repair but is deregulated …

Cardiovascular diseases (CVDs) are multifactorial chronic diseases and have the highest
rates of morbidity and mortality worldwide. The ubiquitin–proteasome system (UPS) plays a …

Tumor recurrence is a mechanism triggered in sparse populations of cancer cells that
usually remain in a quiescent state after strict stress and/or therapeutic factors, which is …

Epithelial‐to‐mesenchymal transition (EMT) is a complex biological process that occurs
during normal embryogenesis and in certain pathological conditions, particularly in cancer …

Purpose In this study, we evaluated the biological role of miRNA-31-5p in papillary thyroid
cancer (PTC). Methods By using the real-time PCR, we measured miRNA-31-5p expression …