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Flaviviruses are group of single stranded RNA viruses that cause severe endemic infection
and epidemics on a global scale. It presents a significant health impact worldwide and the …

The recent emergence and spread of dengue hemorrhagic fever in the Americas have been
a major source of concern. Efforts to control this disease are dependent on understanding …

Dengue virus is an emerging global health threat. The major envelope glycoprotein, E,
mediates viral attachment and entry by membrane fusion. Antibodies that bind but fail to …

Antibody responses generated by mice to the dengue-2 virus NS1 protein (D-2V NS1) were
influenced by MHC class II (IA) haplotype but each antiserum cross-reacted with human …

Dengue viral infection has become an increasing global health concern with over two-fifths
of the world's population at risk of infection. It is the most rapidly spreading vector borne …

The flavivirus E glycoprotein, the primary antigen that induces protective immunity, is
essential for membrane fusion and mediates binding to cellular receptors. Human flavivirus …

Although dengue (DEN) virus is the etiologic agent of dengue fever, the most prevalent
vector-borne viral disease in the world, precise information on the antigenic structure of the …

To elucidate the processes controlling the emergence and spread of dengue-2 virus (DEN-
2) we examined the evolution of viral isolates sampled from both local (Viet Nam) and global …

The increased activity of Dengue virus in the tropical regions of the world and the recent
movement of West Nile virus from the eastern to the western hemisphere emphasize the fact …