Systemic sclerosis (SSc) is a severe auto-immune disease, characterized by vasculopathy
and fibrosis of connective tissues. SSc has a high morbidity and mortality and unfortunately …

Systemic sclerosis (SSc) is a chronic immune-mediated connective tissue disease with
heterogeneous organ involvement. New classification criteria were developed allowing …

Systemic sclerosis (SSc) is a complex autoimmune connective tissue disease which is
characterised by autoimmunity, widespread tissue fibrosis of the skin and internal organs …

Abstract Objectives In SSc patients, disease specific determinants that influence health-
related quality of life (HRQoL) over time have not been described. We aim to, in patients with …

Systemic sclerosis (SSc) is an intractable autoimmune disease with unmet medical needs.
Conventional immunosuppressive therapies have modest efficacy and obvious side effects …

Abstract Background Systemic sclerosis (SSc) is associated with a variability of mortality
rates in the literature. Objective To determine the mortality and its predictors in a long-term …

Aim Patients with systemic sclerosis (SSc) are at increased risk of cancer, a growing cause
of non–SSc-related death among these patients. We analyzed the increased cancer risk …

ABSTRACT Objectives: Systemic sclerosis (SSc) is a rare, chronic connective tissue disease
involving multiple organ systems, including the eye. We evaluated the detailed clinical …

Background We aimed to evaluate sex-specific risk of anti-topoisomerase I antibodies (ATA)
on mortality, diffuse cutaneous systemic sclerosis, interstitial lung disease, and pulmonary …

Objective There is still a great deal to learn about the influence of sex in systemic sclerosis
(SSc). In this respect, national registries provide large and homogeneous patient cohorts for …