Breast cancer has ranked number one cancer among Indian females with age adjusted rate
as high as 25.8 per 100,000 women and mortality 12.7 per 100,000 women. Data reports …

The incidence of breast cancer is low in India, but rising. Breast cancer is the commonest
cancer of urban Indian women and the second commonest in the rural women. Owing to the …

The integrity of genomes is constantly threatened by problems encountered by the
replication fork. BRCA1, BRCA2 and a subset of Fanconi anaemia proteins protect stalled …

Breast cancer (BC) is the most common cancer of women all over the world. BRCA1 and
BRCA2 gene mutations comprise the most important genetic susceptibility of BC. Except for …

Approximately 5%–10% of breast cancers are due to genetic predisposition caused by
germline mutations; the most commonly tested genes are BRCA1 and BRCA2 mutations …

Purpose Breast and/or ovarian cancers are among the most common cancers in women
across the world. In the Indian population, the healthcare burden of breast and/or ovarian …

Abstract Among Asian countries, Pakistan has the highest rates of breast and ovarian
cancer. To assess the contribution of the BRCA1 and BRCA2 germ line mutations to these …

Breast cancer is the most prevalent cancer in Asian females, and the incidence of breast
cancer has been increasing in Asia. Be cause Asian patients develop breast cancer at a …

Breast and/or ovarian cancer (BOC) are among the most frequently diagnosed forms of
hereditary cancers and leading cause of death in India. This emphasizes on the need for a …

Background A large number of distinct mutations in the BRCA1 and BRCA2 genes have
been reported worldwide, but little is known regarding the role of these inherited …