Oral candidiasis: A disease of opportunity

T Vila, AS Sultan, D Montelongo-Jauregui… - Journal of fungi, 2020 - mdpi.com
Oral candidiasis, commonly referred to as “thrush,” is an opportunistic fungal infection that
commonly affects the oral mucosa. The main causative agent, Candida albicans, is a highly …

Current antimycotics, new prospects, and future approaches to antifungal therapy

G Wall, JL Lopez-Ribot - Antibiotics, 2020 - mdpi.com
Fungal infections represent an increasing threat to a growing number of immune-and
medically compromised patients. Fungi are eukaryotic organisms and, as such, there is a …

ESICM/ESCMID task force on practical management of invasive candidiasis in critically ill patients

I Martin-Loeches, M Antonelli, M Cuenca-Estrella… - Intensive care …, 2019 - Springer
Introduction The term invasive candidiasis (IC) refers to both bloodstream and deep-seated
invasive infections, such as peritonitis, caused by Candida species. Several guidelines on …

Effect of silver nanoparticles on Candida albicans biofilms: an ultrastructural study

HH Lara, DG Romero-Urbina, C Pierce… - Journal of …, 2015 - Springer
Background Candida albicans is the most common pathogenic fungus isolated in
bloodstream infections in hospitalized patients, and candidiasis represents the fourth most …

Synergistic combinations of antifungals and anti-virulence agents to fight against Candida albicans

J Cui, B Ren, Y Tong, H Dai, L Zhang - Virulence, 2015 - Taylor & Francis
Candida albicans, one of the pathogenic Candida species, causes high mortality rate in
immunocompromised and high-risk surgical patients. In the last decade, only one new class …

Overcoming antifungal resistance

A Srinivasan, JL Lopez-Ribot… - Drug Discovery Today …, 2014 - Elsevier
Fungal infections have become one of the major causes of morbidity and mortality in
immunocompromised patients. Despite increased awareness and improved treatment …

Components of the calcium-calcineurin signaling pathway in fungal cells and their potential as antifungal targets

S Liu, Y Hou, W Liu, C Lu, W Wang, S Sun - Eukaryotic cell, 2015 - Am Soc Microbiol
In recent years, the emergence of fungal resistance has become frequent, partly due to the
widespread clinical use of fluconazole, which is minimally toxic and effective in the …

Natural antimicrobial peptides as inspiration for design of a new generation antifungal compounds

M Bondaryk, M Staniszewska, P Zielińska… - Journal of fungi, 2017 - mdpi.com
Invasive fungal infections are associated with high mortality rates, despite appropriate
antifungal therapy. Limited therapeutic options, resistance development and the high …

Non-albicans Candida Species: Immune Response, Evasion Mechanisms, and New Plant-Derived Alternative Therapies

M Gómez-Gaviria, U Ramírez-Sotelo, HM Mora-Montes - Journal of Fungi, 2022 - mdpi.com
Fungal infections caused by Candida species have become a constant threat to public
health, especially for immunocompromised patients, who are considered susceptible to this …

Enhancing the antifungal activity of griseofulvin by incorporation a green biopolymer-based nanocomposite

A Shehabeldine, H El-Hamshary, M Hasanin… - Polymers, 2021 - mdpi.com
Fungal biofilms have caused several medical problems, resulting in significant morbidity and
mortality as well as poor response to antifungal drugs. The current study was designed to …