[HTML][HTML] Targeting necroptosis: a novel therapeutic option for retinal degenerative diseases

Q Zhang, X Hu, W Zhao, X Ban, Y Li… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
The discovery of the necroptosis, a form of regulated necrosis that is mediated by receptor-
interacting protein kinase 1 (RIPK1), RIPK3, and mixed-lineage kinase domain-like …

Comprehensive variant spectrum of the CNGA3 gene in patients affected by achromatopsia

M Solaki, B Baumann, P Reuter, S Andreasson… - Human …, 2022 - Wiley Online Library
Achromatopsia (ACHM) is a congenital cone photoreceptor disorder characterized by
impaired color discrimination, low visual acuity, photosensitivity, and nystagmus. To date, six …

[HTML][HTML] Geometrical scaling of the developing eye and photoreceptors and a possible relation to emmetropization and myopia

B Vohnsen - Vision Research, 2021 - Elsevier
In this study the role of vergence in relation to age-dependent scaling of eye and
photoreceptor parameters is studied. The underlying hypothesis is that the size and packing …

The role of retinal dysfunction in myopia development

Y Huang, X Chen, J Zhuang, K Yu - Cellular and Molecular Neurobiology, 2023 - Springer
Myopia is a refractive disorder arising from a mismatch between refractive power and
relatively long axial length of the eye. With its dramatically increasing prevalence, myopia …

Pre-occupancy evaluation of a virtual music school classroom: Influence of color and type of lighting on music performers

JLG Sirvent, D Fernández-Sotos… - Building and …, 2023 - Elsevier
The built environment has the potential to influence human emotions, behaviors, and
cognitive abilities. This study examined the influence of classroom architectural design …

CNGB3 Missense Variant Causes Recessive Achromatopsia in Original Braunvieh Cattle

IM Häfliger, E Marchionatti, M Stengård… - International journal of …, 2021 - mdpi.com
Sporadic occurrence of inherited eye disorders has been reported in cattle but so far
pathogenic variants were found only for rare forms of cataract but not for retinopathies. The …

Outer retinal transduction by AAV2-7m8 following intravitreal injection in a sheep model of CNGA3 achromatopsia

M Ross, A Obolensky, E Averbukh, M Desrosiers… - Gene Therapy, 2022 - nature.com
Sheep carrying a mutated CNGA3 gene exhibit diminished cone function and provide a
naturally occurring large animal model of achromatopsia. Subretinal injection of a vector …

Role of biometals in activation of immune cum inflammatory response in ovine ageing eye: a potential model for understanding human geriatric eye diseases

SU Nabi, A Jan, S Muzamil, R Razaq, A Muhee… - Biometals, 2021 - Springer
The present study was designed to evaluate the age-related changes in biometal and
antimicrobial peptide (cathelicidin) concentration and their role in oxidative cum pro …

The causal mutation in ARR3 gene for high myopia and progressive color vision defect

L Gu, P Cong, Q Ning, B Jiang, J Wang, H Cui - Scientific Reports, 2023 - nature.com
The ARR3 gene, also known as cone arrestin, belongs to the arrestin family and is
expressed in cone cells, inactivating phosphorylated-opsins and preventing cone signals …

A retinoscopic survey of donkeys and goats

O Pe'er, L Gantz, E Gal, R Ofri - Veterinary Ophthalmology, 2023 - Wiley Online Library
Purpose Assess the refractive states of donkeys and goats. Methods Forty‐two donkeys and
28 goats were enrolled. The mean±SD ages were 7.68±7.33 years for donkeys and …