Cellular responses to environmental cues involve the mobilization of GTPases, protein
kinases and phosphoprotein phosphatases. The spatial organization of these signalling …

Dual‐specificity tyrosine‐regulated kinases (DYRKs) comprise a family of protein kinases
within the CMGC group of the eukaryotic kinome. Members of the DYRK family are found in …

Abscisic acid (ABA) is an essential hormone for plants to survive environmental stresses. At
the center of the ABA signaling network is a subfamily of type 2C protein phosphatases …

In sexual reproduction of most animals, the spermatozoon provides DNA and centrioles,
together with some cytoplasm and organelles, to the oocyte that is being fertilized. Paternal …

Dual‐specificity tyrosine phosphorylation‐regulated kinase 1A (DYRK1A) is a protein kinase
with diverse functions in neuronal development and adult brain physiology. Higher than …

Pseudophosphatases and pseudokinases are increasingly viewed as integral elements of
signaling pathways, and there is mounting evidence that they have frequently retained the …

Mitogen-activated protein kinase (MAPK) signaling pathways are highly conserved
regulators of eukaryotic cell function. These enzymes regulate many biological processes …

Production of functional eggs requires meiosis to be coordinated with developmental
signals. Oocytes arrest in prophase I to permit oocyte differentiation, and in most animals, a …

Retrograded starch is known to be resistant to digestion. We used enzyme kinetic
experiments to examine how retrogradation of starch affects amylolysis catalysed by porcine …

Highlights•Pseudoenzymes are structural, but catalytically defective, homologs of
enzymes.•Examples of pseudoenzymes have been identified in all kingdoms of …