Roger D. Kornberg* and Yahli Lorch Department of Structural Biology Stanford University
School of Medicine Stanford, California 94305 model building and other predictive structural …

Histone proteins play essential structural and functional roles in the transition between
active and inactive chromatin states. Although histones have a high degree of conservation …

The structure of the octameric histone core of the nucleosome has been determined by x-ray
crystallography to a resolution of 3.1 A. The histone octamer is a tripartite assembly in which …

This book covers material that could be included in a one-quarter or one-semester course in
bioinorganic chemistry for graduate students and advanced undergraduate students in …

The crystal structure of the nucleosome core particle has been solved to 7 Å resolution. The
right-handed B-DNA superhelix on the outside contains several sharp bends and makes …

A review is given about research for elucidating the structures of viruses and chromatin. In
biochemical processes which take place in a living cell, large molecules are involved such …

The ring closure probability, or j factor, has been measured for DNA restriction fragments of
defined sequence bearing EcoRI cohesive ends and ranging in size from 126 to 4361 base …

When quiescent cells are stimulated with growth factors, phorbol esters, okadaic acid, or
protein synthesis inhibitors, the early-response genes, which include c-fos and c-jun, are …

The histone octamer core of the nucleosome is a protein superhelix of four spirally arrayed
histone dimers. The cylindrical face of this superhelix is marked by intradimer and interdimer …

The three-dimensional chromosome topography in an intact nucleus has been determined
using fluorescently stained Drosophila polytene chromosomes, optical fluorescence …