5-methylcytosine modification by Plasmodium NSUN2 stabilizes mRNA and mediates the development of gametocytes

M Liu, G Guo, P Qian, J Mu, B Lu… - Proceedings of the …, 2022 - National Acad Sciences
5-methylcytosine (m5C) is an important epitranscriptomic modification involved in
messenger RNA (mRNA) stability and translation efficiency in various biological processes …

Comparative proteomics of vesicles essential for the egress of Plasmodium falciparum gametocytes from red blood cells

J Sassmannshausen, S Bennink, U Distler… - Molecular …, 2024 - Wiley Online Library
Transmission of malaria parasites to the mosquito is mediated by sexual precursor cells, the
gametocytes. Upon entering the mosquito midgut, the gametocytes egress from the …

Identification of a novel AP2 transcription factor in zygotes with an essential role in Plasmodium ookinete development

T Nishi, I Kaneko, S Iwanaga, M Yuda - PLoS pathogens, 2022 - journals.plos.org
The sexual phase of Plasmodium represents a crucial step in malaria transmission, during
which these parasites fertilize and form ookinetes to infect mosquitoes. Plasmodium …

A time point proteomic analysis reveals protein dynamics of Plasmodium oocysts

CMF Preira, E Pizzi, F Fratini, F Grasso… - Molecular & Cellular …, 2024 - ASBMB
The oocyst is a sporogonic stage of Plasmodium development that takes place in the
mosquito midgut in about 2 weeks. The cyst is protected by a capsule of unknown …

Characterization of PSOP26 as an ookinete surface antigen with improved transmission-blocking activity when fused with PSOP25

P Wang, X Jiang, J Bai, F Yang, X Yu, Y Wu… - Parasites & …, 2022 - Springer
Abstract Background The Plasmodium zygote-to-ookinete developmental transition is an
essential step for establishing an infection in the mosquito vector, and antigens expressed …

Identification of a novel protein localized to the crystalloid of the Plasmodium ookinete

M Tachibana, M Baba, H Iriko, N Shinzawa… - Parasitology …, 2024 - Elsevier
Reducing Plasmodium parasite transmission via the mosquito vector is a promising strategy
for malaria control and elimination in endemic regions. In the mosquito midgut after the …

Comparative proteomics of vesicles essential for the egress of Plasmodium falciparum gametocytes from red blood cell

G Pradel, J Sassmannshausen, S Bennink… - Authorea …, 2023 - advance.sagepub.com
The tropical disease malaria is caused by protozoan parasites of the genus Plasmodium.
The disease is characterized by symptoms like high fever, anemia, nausea, and respiratory …

Identification of a novel AP2 transcription factor in zygotes with an essential role in Plasmodium ookinete development

西翔, ニシツバサ - mie-u.repo.nii.ac.jp
The sexual phase of Plasmodium represents a crucial step in malaria transmission, during
which these parasites fertilize and form ookinetes to infect mosquitoes. Plasmodium …