Epigenetics regulates gene expression and has been confirmed to play a critical role in a
variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease …

Epigenome editing has rapidly evolved in recent years, with diverse applications that
include elucidating gene regulation mechanisms, annotating coding and noncoding …

Human health is determined by the interaction of our environment with the genome,
epigenome, and microbiome, which shape the transcriptomic, proteomic, and metabolomic …

Since its first appearance, CRISPR–Cas9 has been developed extensively as a
programmable genome-editing tool, opening a new era in plant genome engineering …

Epigenome editing methods enable the precise manipulation of epigenetic modifications,
such as histone posttranscriptional modifications (PTMs), for uncovering their biological …

Enhancing plant resistance against pests and diseases by priming plant immunity is an
attractive concept for crop protection because it provides long-lasting broad-spectrum …

Microorganisms have gained defense systems during the lengthy process of evolution over
millions of years. Such defense systems can protect them from being attacked by invading …

The critical role of dysregulated epigenetic pathways in cancer genesis, development, and
therapy has typically been established as a result of scientific and technical innovations in …

Abstract Purpose of the Review Exposure to essential and non-essential metals is
widespread. Metals exposure is linked to epigenetic, particularly DNA methylation …

Active DNA demethylation plays a crucial role in eukaryotic gene imprinting and
antagonizing DNA methylation. The plant-specific REPRESSOR OF SILENCING …