Tumors are comprised of both cancer cells and surrounding stromal components. As an
essential part of the tumor microenvironment, the tumor stroma is highly dynamic …

Mesenchymal stem cells (MSCs) are among the most frequently used cell type for
regenerative medicine. A large number of studies have shown the beneficial effects of MSC …

The insufficient and unspecific target of traditional therapeutic approaches in cancer
treatment often leads to therapy resistance and cancer recurrence. Over the past decades …

Cell-based drug delivery systems (DDSs) have received attention recently because of their
unique biological properties and self-powered functions, such as excellent biocompatibility …

Osteosarcoma (OS) is a highly malignant tumor occurring in bone tissue with a high
propensity to metastasize, and its underlying mechanisms remain largely elusive. The OS …

The use of tailored medication delivery in cancer treatment has the potential to increase
efficacy while decreasing unfavourable side effects. For researchers looking to improve …

Bone diseases, such as bone cancer, bone infection and osteoporosis, constitute a major
issue for modern societies as a consequence of their progressive ageing. Even though …

Synthetic cells are engineered vesicles that can mimic one or more salient features of life.
These features include directed localization, sense‐and‐respond behavior, gene …

Tumor metastasis and recurrence is one of the biggest problems in curing cancers. Due to
the difficulty in complete removal of the primary tumor in traditional surgeries and the poor …

The strategy of using mesenchymal stem cells (MSCs) as a living carrier for active delivery of
therapeutic agents targeting tumor sites has been attempted in a wide range of studies to …