[HTML][HTML] Neural control of the lower urinary tract

WC de Groat, D Griffiths… - Comprehensive Physiology, 2015 - ncbi.nlm.nih.gov
This article summarizes anatomical, neurophysiological, pharmacological, and brain
imaging studies in humans and animals that have provided insights into the neural circuitry …

Urothelial signaling

L Birder, KE Andersson - Physiological reviews, 2013 - journals.physiology.org
The urothelium, which lines the inner surface of the renal pelvis, the ureters, and the urinary
bladder, not only forms a high-resistance barrier to ion, solute and water flux, and …

The urothelium: life in a liquid environment

MG Dalghi, N Montalbetti, MD Carattino… - Physiological …, 2020 - journals.physiology.org
The urothelium, which lines the renal pelvis, ureters, urinary bladder, and proximal urethra,
forms a high-resistance but adaptable barrier that surveils its mechanochemical …

Pharmacology of the lower urinary tract

KE Andersson, C Gratzke - Textbook of the neurogenic bladder, 2008 - taylorfrancis.com
Introduction The normal bladder functions, storage and elimination of urine, are based on a
coordinated interplay of reciprocal contraction and relaxation of the bladder and the outflow …

Cell biology and physiology of the uroepithelium

P Khandelwal, SN Abraham… - American Journal of …, 2009 - journals.physiology.org
The uroepithelium sits at the interface between the urinary space and underlying tissues,
where it forms a high-resistance barrier to ion, solute, and water flux, as well as pathogens …

Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1

LA Birder, Y Nakamura, S Kiss, ML Nealen… - Nature …, 2002 - nature.com
In the urinary bladder, the capsaicin-gated ion channel TRPV1 is expressed both within
afferent nerve terminals and within the epithelial cells that line the bladder lumen. To …

The uroepithelium: not just a passive barrier

G Apodaca - Traffic, 2004 - Wiley Online Library
The uroepithelium lines the inner surface of the renal pelvis, the ureters, and the urinary
bladder, where it forms a tight barrier that allows for retention of urine, while preventing the …

Vanilloid receptor expression suggests a sensory role for urinary bladder epithelial cells

LA Birder, AJ Kanai, WC De Groat… - Proceedings of the …, 2001 - National Acad Sciences
Materials and Methods Reverse Transcription–PCR. Poly (A) RNA was isolated from tissue
or cultured cells by homogenization in Trizol (Life Technologies, Grand Island, NY) followed …

Mechanisms of disease: involvement of the urothelium in bladder dysfunction

LA Birder, WC De Groat - Nature clinical practice Urology, 2007 - nature.com
Although the urinary bladder urothelium has classically been thought of as a passive barrier
to ions and solutes, a number of novel properties have been recently attributed to urothelial …

Integrative control of the lower urinary tract: preclinical perspective

WC de Groat - British journal of pharmacology, 2006 - Wiley Online Library
Storage and periodic expulsion of urine is regulated by a neural control system in the brain
and spinal cord that coordinates the reciprocal activity of two functional units in the lower …