Biomolecular condensates are dynamic liquid droplets through intracellular liquid–liquid
phase separation that function as membraneless organelles, which are highly involved in …

Cells achieve high spatiotemporal control over biochemical processes through
compartmentalization to membrane-bound as well as membraneless organelles that …

While the cellular cytosol and organelles contain attractive targets for disease treatments, it
remains a challenge to deliver therapeutic biomacromolecules to these sites. This is due to …

Intrinsically disordered protein α-synuclein (αS) is implicated in Parkinson's disease due to
its aberrant aggregation propensity. In a bid to identify the traits of its aggregation, here we …

Liquid–liquid phase separation (LLPS) plays a key role in the compartmentalization of cells
via the formation of biomolecular condensates. Here, we combined atomistic molecular …

Biomolecular condensates formed via phase separation of intrinsically disordered
proteins/regions (IDPs/IDRs) and nucleic acids are associated with cell physiology and …

Biomolecular condensates form by phase separation of biological polymers. The cellular
functions of the resulting membraneless organelles are closely linked to their physical …

Intrinsically disordered peptides (IDPs) have been found to undergo liquid–liquid phase
separation (LLPS) and produce complex coacervates that play numerous regulatory roles in …

Proteins with prion-like domains (PLDs) are involved in neurodegeneration-associated
aggregation and are prevalent in liquid-like membrane-less organelles. These PLDs contain …

Metalloproteins make up a class of proteins that incorporate metal ions into their structures,
enabling them to perform essential functions in biological systems, such as catalysis and …