Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …

Protein semisynthesis—defined herein as the assembly of a protein from a combination of
synthetic and recombinant fragments—is a burgeoning field of chemical biology that has …

The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has created global health and
economic emergencies. SARS-CoV-2 viruses promote their own spread and virulence by …

Tight junctions are complex supramolecular entities composed of integral membrane
proteins, membrane-associated and soluble cytoplasmic proteins engaging in an intricate …

WNT/β-catenin signaling orchestrates various physiological processes, including embryonic
development, growth, tissue homeostasis, and regeneration. Abnormal WNT/β-catenin …

Small linear motifs targeting protein interacting domains called PSD‐95/Dlg/ZO‐1 (PDZ)
have been identified at the C terminus of the severe acute respiratory syndrome coronavirus …

Therapies for stroke have remained elusive in the past despite the great relevance of this
pathology. However, recent results have provided strong evidence that postsynaptic density …

Since 2003, the world has been confronted with three new betacoronaviruses that cause
human respiratory infections: SARS-CoV, which causes severe acute respiratory syndrome …

The first reported receptor for SARS-CoV-2 on host cells was the angiotensin-converting
enzyme 2 (ACE2). However, the viral spike protein also has an RGD motif, suggesting that …

Syndecan-1 (SDC1, CD138) is one of the heparan sulfate proteoglycans and is essential for
maintaining normal cell morphology, interacting with the extracellular and intracellular …