Mechanisms and regulation of RNA condensation in RNP granule formation

D Tauber, G Tauber, R Parker - Trends in biochemical sciences, 2020 - cell.com
Ribonucleoprotein (RNP) granules are RNA–protein assemblies that are involved in
multiple aspects of RNA metabolism and are linked to memory, development, and disease …

Trans-Acting Small RNAs and Their Effects on Gene Expression in Escherichia coli and Salmonella enterica

J Hör, G Matera, J Vogel, S Gottesman, G Storz - EcoSal Plus, 2020 - Am Soc Microbiol
The last few decades have led to an explosion in our understanding of the major roles that
small regulatory RNAs (sRNAs) play in regulatory circuits and the responses to stress in …

RNA-RNA interactomes of ProQ and Hfq reveal overlapping and competing roles

S Melamed, PP Adams, A Zhang, H Zhang, G Storz - Molecular cell, 2020 - cell.com
Base pairing RNAs modulate gene expression in all studied organisms. In many bacteria,
the base pairing between most small regulatory RNAs (sRNAs) and their targets is mediated …

RNA folding and functions of RNA helicases in ribosome biogenesis

V Mitterer, B Pertschy - RNA biology, 2022 - Taylor & Francis
Eukaryotic ribosome biogenesis involves the synthesis of ribosomal RNA (rRNA) and its
stepwise folding into the unique structure present in mature ribosomes. rRNA folding starts …

How does RNA fold dynamically?

DZ Bushhouse, EK Choi, LM Hertz, JB Lucks - Journal of molecular biology, 2022 - Elsevier
Recent advances in interrogating RNA folding dynamics have shown the classical model of
RNA folding to be incomplete. Here, we pose three prominent questions for the field that are …

RNA-binding proteins driving the regulatory activity of small non-coding RNAs in bacteria

AP Quendera, AF Seixas, RF Dos Santos… - Frontiers in molecular …, 2020 - frontiersin.org
Small non-coding RNAs (sRNAs) are critical post-transcriptional regulators of gene
expression. Distinct RNA-binding proteins (RBPs) influence the processing, stability and …

A high-resolution transcriptome map identifies small RNA regulation of metabolism in the gut microbe Bacteroides thetaiotaomicron

D Ryan, L Jenniches, S Reichardt, L Barquist… - Nature …, 2020 - nature.com
Bacteria of the genus Bacteroides are common members of the human intestinal microbiota
and important degraders of polysaccharides in the gut. Among them, the species …

Identification of RNA structures and their roles in RNA functions

X Cao, Y Zhang, Y Ding, Y Wan - Nature Reviews Molecular Cell …, 2024 - nature.com
The development of high-throughput RNA structure profiling methods in the past decade has
greatly facilitated our ability to map and characterize different aspects of RNA structures …

Cryo-EM reveals an entangled kinetic trap in the folding of a catalytic RNA

SL Bonilla, Q Vicens, JS Kieft - Science Advances, 2022 - science.org
Functional RNAs fold through complex pathways that can contain misfolded “kinetic traps.” A
complete model of RNA folding requires understanding the formation of these misfolded …

A roadmap for rRNA folding and assembly during transcription

ML Rodgers, SA Woodson - Trends in biochemical sciences, 2021 - cell.com
Ribonucleoprotein (RNP) assembly typically begins during transcription when folding of the
newly synthesized RNA is coupled with the recruitment of RNA-binding proteins (RBPs) …