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Regulatory T cells (Tregs) and T helper 17 cells (Th17) are two CD4+ T cell subsets with
antagonist effects. Th17 cells promote inflammation, whereas Tregs are crucial in …

Acute lung injury (ALI) is characterized by rapid alveolar injury, inflammation, cytokine
induction, and neutrophil accumulation. Although early events in the pathogenesis of ALI …

Surviving a given infection requires the generation of a controlled immune response. Failure
to establish or restore homeostatic conditions during or following the onset of an infection …

Each microenvironment requires a specific set of regulatory elements that are finely and
constantly tuned to maintain local homeostasis. Various populations of regulatory T cells …

Evidence has increasingly shown that the lungs are a major site of immune regulation. A
robust and highly regulated immune response in the lung protects the host from pathogen …

Rationale: Pulmonary arterial hypertension (PAH) is an incurable disease associated with
viral infections and connective tissue diseases. The relationship between inflammation and …

Abstract Regulatory Foxp3+ CD4 T cells (Tregs) prevent spontaneous inflammation in the
lungs, inhibit allergic and asthmatic responses, and contribute to tolerance to inhaled …

A more detailed understanding of Treg cells in COVID‐19 infection will broaden our
knowledge of the COVID‐19 immunopathology and give us more insight into the curative …

Infectious agents have intimately co-evolved with the host immune system, acquiring a
portfolio of highly sophisticated mechanisms to modulate immunity. Among the common …