Aerobic, or endurance, exercise is an energy requiring process supported primarily by
energy from oxidative adenosine triphosphate synthesis. The consumption of oxygen and …

Cardiopulmonary exercise testing (CPET) remains poorly understood and, consequently,
largely underused in respiratory medicine. In addition to a widespread lack of knowledge of …

Low resting inspiratory capacity (IC) and low maximal inspiratory pressure (MIP) have
previously been linked to exertional dyspnea, exercise limitation, and poor survival in …

The functional disturbances driving “out-of-proportion” dyspnoea in patients with fibrosing
interstitial lung disease (f-ILD) showing only mild restrictive abnormalities remain poorly …

Rationale: It is increasingly recognized that adults with preserved ratio impaired spirometry
(PRISm) are prone to increased morbidity. However, the underlying pathophysiological …

Cardiopulmonary exercise testing (CPET) is a comprehensive and invaluable assessment
used to identify the mechanisms that limit exercise capacity. However, its interpretation …

Cardiopulmonary exercise testing (CPET) has traditionally included ventilatory and
metabolic measurements alongside electrocardiographic characterization; however …

Background Exercise intolerance, desaturation, and dyspnea are common features in
patients with chronic obstructive pulmonary disease (COPD). At altitude, the barometric …

Objective To assess if dynamic hyperinflation is an independent risk factor for mortality and
severe exacerbations in COPD patients. Methods A cohort of 141 patients with stable COPD …

Abstract Purpose Hypermobile Ehlers–Danlos syndrome (hEDS) is a connective tissue
disorder with many different symptoms such as pain, fatigue, dysautonomia, or respiratory …