In recent times, there has been a considerable increase in the use of aortic bioprostheses
(vs. mechanical prostheses) for treating aortic valve disease, and this tendency is likely to …

The implantation of bioprosthetic heart valves (BHVs) is increasingly becoming the treatment
of choice in patients requiring heart valve replacement surgery. Unlike mechanical heart …

The transplantation (implantation) of xenograft heart valves into humans has been carried
out for> 50 years. There has been considerable research into making this form of …

Electrospun nanofibers are promising bone tissue scaffolds that support bone healing due to
the body's structural similarity to the extracellular matrix (ECM). However, the insufficient …

Background—Glutaraldehyde fixation (GF) decreases but likely does not eliminate the
antigenicity of bioprosthetic heart valves. Rejection (with secondary dystrophic calcification) …

Scaffolds for heart valve tissue engineering must function immediately after implantation but
also need to tolerate cell infiltration and gradual remodeling. We hypothesized that …

Although heart valve replacement is among the most common cardiovascular surgical
procedures, their outcome is often difficult to predict. One of the reasons is the design and …

Bioprosthetic heart valves (BHVs) originating from pigs are extensively used for heart valve
replacement in clinics. However, recipient immune responses associated with chronic …

Glutaraldehyde‐fixed bioprosthetic heart valves (GBHV s), derived from pigs or cows,
undergo structural valve deterioration (SVD) over time, with calcification and eventual …

Glycosaminoglycans (GAGs) are important structural and functional components in native
aortic heart valves and in glutaraldehyde (Glut)-fixed bioprosthetic heart valves (BHVs) …