Current evidence strongly suggests that aberrant activation of the NF-κB signalling pathway
is associated with carcinogenesis. A number of key cellular processes are governed by the …

NF-κB (nuclear factor-kappa B) is a transcription complex crucial for host defense mediated
by innate and adaptive immunity, where canonical NF-κB signaling, mediated by nuclear …

Background The nuclear factor κ light-chain enhancer of activated B cells (NF-κB) signaling
pathway is a key regulator of immune responses. Accordingly, mutations in several NF-κB …

Abstract MicroRNA-146a (miR-146a) has been shown to play an important role in the
regulation of inflammatory innate immune responses, and found to be differentially …

Melanoma is the most aggressive skin malignancy with increasing incidence worldwide.
Pannexin1 (PANX1), a member of the pannexin family of channel-forming glycoproteins …

Several studies were published last year which focused on the epidemiology,
immunopathogenesis, genetics, clinical manifestations and management of Behçet's …

Behçet´ s disease (BD) is a heterogeneous condition consisting of idiopathic systemic
vasculitis affecting large and small blood vessels of different types (ie, arteries, veins, or …

Behçet's disease (BD) is a heterogeneous multi‐organ disorder in search of a unified
pathophysiological theory and classification. The disease frequently has overlapping …

Behçet's disease (BD) is a polygenic condition with a complex immunopathogenetic
background and challenging diagnostic and therapeutic concepts. Advances in genomic …

MiRNAs and NFKB1 are well-known immune response and inflammation regulators. MiRNA
gene polymorphisms may affect miRNA biogenesis and function and, may thus, lead to …