High Fischer ratio oligopeptides from hard-shelled mussel: Preparation and hepatoprotective effect against acetaminophen-induced liver injury in mice

SL Zheng, YZ Wang, YQ Zhao, CF Chi, WY Zhu… - Food Bioscience, 2023 - Elsevier
Abstract High Fischer ratio oligopeptides (HFOPs) have a variety of physiological activities,
but there are few literatures reporting the hepatoprotective effects of HFOPs against …

[HTML][HTML] Acetaminophen-induced apoptosis: Facts versus fiction

H Jaeschke, A Ramachandran - Journal of Clinical and …, 2020 - ncbi.nlm.nih.gov
An overdose of the widely used analgesic acetaminophen (APAP) is the most common
cause of acute liver failure in the western world and hence is a clinically significant problem …

Protection of taraxasterol against acetaminophen-induced liver injury elucidated through network pharmacology and in vitro and in vivo experiments

B Ge, R Sang, W Wang, K Yan, Y Yu, L Kong, M Yu… - Phytomedicine, 2023 - Elsevier
Background: Drug-induced liver injury (DILI) is primarily caused by drugs or their
metabolites. Acetaminophen (APAP) is an over-the-counter antipyretic analgesic that …

Irbesartan reprofiling for the amelioration of ethanol-induced gastric mucosal injury in rats: Role of inflammation, apoptosis, and autophagy

HH Arab, AH Eid, AAK El-Sheikh, ESA Arafa… - Life Sciences, 2022 - Elsevier
Background Pronounced anti-inflammatory and anti-apoptotic features have been
characterized for the angiotensin receptor blocker irbesartan. Yet, its effect on ethanol …

[HTML][HTML] Diacerein ameliorates acetaminophen hepatotoxicity in rats via inhibiting HMGB1/TLR4/NF-κB and upregulating PPAR-γ signal

GA Mohamed Kamel, E Harahsheh… - Molecular Biology Reports, 2022 - Springer
Background Acetaminophen (APAP) is a worldwide antipyretic as well as an analgesic
medication. It has been extensively utilized during the outbreak of coronavirus 2019 (COVID …

Potential anti-inflammatory effect of dapagliflozin in HCHF diet-induced fatty liver degeneration through inhibition of TNF-α, IL-1β, and IL-18 in rat liver

MK ElMahdy, MG Helal, TM Ebrahim - International Immunopharmacology, 2020 - Elsevier
Non-alcoholic fatty liver (NAFLD) is accompanied by an increased expression of oxidative
stress parameters, in addition to the inflammatory cytokines; tumor necrosis factor alpha …

[HTML][HTML] Capsaicin protects against septic acute liver injury by attenuation of apoptosis and mitochondrial dysfunction

A Ghorbanpour, S Salari, T Baluchnejadmojarad… - Heliyon, 2023 - cell.com
Capsaicin is the main pungent bioactive constituent in red chili with promising therapeutic
properties due to its anti-oxidative and anti-inflammatory effects. No evidence exists on the …

Hepatoprotective effect of myricetin following lipopolysaccharide/dgalactosamine: involvement of autophagy and sirtuin 1

A Rostami, T Baluchnejadmojarad… - Current Molecular …, 2023 - ingentaconnect.com
Background: Acute liver injury (ALI) is a critical and fatal disorder associated with excessive
oxidative stress and inflammation, ultimately leading to the death of hepatocytes. Myricetin is …

[HTML][HTML] Moringa oleifera Lam. leaf extract mitigates carbon tetrachloride-mediated hepatic inflammation and apoptosis via targeting oxidative stress and toll-like …

SM Fathy, MS Mahmoud - Food Science and Human Wellness, 2021 - Elsevier
Carbon tetrachloride (CCl 4) is a hepatotoxin that triggers liver damage. This study aimed to
evaluate the protective effect of phytochemicals detected in Moringa oleifera Lam. leaf …

[HTML][HTML] Preventive effects of Chinese sumac fruits against acetaminophen-induced liver injury in mice via regulating oxidative stress, inflammation and apoptosis

Y Sun, N Ma, X Liu, J Yi, S Cai - Journal of Functional Foods, 2021 - Elsevier
This study aimed to investigate the effects of the phenolic-rich fraction from Chinese sumac
fruits against liver injury induced by acetaminophen in mice and elucidate the potential …