Pharmaceutical solid dosage forms (tablets or capsules) are the predominant form to
administer active pharmaceutical ingredients (APIs) to the patient. Tablets are typically …

Traditionally, the development of a new solid dosage form is formulation-driven and less
focus is put on the design of a specific microstructure for the drug delivery system. However …

Highlights•Cyclodextrins are complexing excipients in tablets mainly for potent
drugs.•Methods to enhance the complexation efficiency decrease the cyclodextrin …

In current study a holistic material characterization approach was proposed and an
extensive raw material property database was developed including a wide variety of APIs …

The selection and design of age-appropriate formulations intended for use in paediatric and
geriatric patients are dependent on multiple factors affecting patient acceptability, safety and …

Abstract Following the first Manufacturing Classification System (MCS) paper, the team
conducted surveys to establish which active pharmaceutical ingredient (API) properties were …

Hydroxypropyl methylcellulose acetate succinate (HPMCAS) has been widely investigated
as a carrier for amorphous solid dispersion (ASD) of poorly water-soluble drugs. However …

In this mini-review, we have critically examined literature aimed at understanding the
mechanisms to the frequently observed phenomenon of loss of tabletability of a powder after …

In this work a continuous direct compression process was developed for a low-dosed drug
product. Each unit operation of the GEA CDC-50 system was thoroughly investigated. This …

In this paper, a compression behavior classification system (CBCS) for direct compression
(DC) pharmaceutical powders is presented. Seven descriptors from a series of compression …